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The establishment of COPD organoids to study host-pathogen interaction reveals enhanced viral fitness of SARS-CoV-2 in bronchi.

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Title: The establishment of COPD organoids to study host-pathogen interaction reveals enhanced viral fitness of SARS-CoV-2 in bronchi.
Authors: Chan LLY; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore. louisa.chanly@ntu.edu.sg., Anderson DE; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore., Cheng HS; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Ivan FX; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Chen S; School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore, Singapore., Kang AEZ; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore., Foo R; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore., Gamage AM; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore., Tiew PY; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Koh MS; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Lee KCH; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Nichol K; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia., Pathinayake PS; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia., Chan YL; School of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW, Australia., Yeo TW; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; National Centre for Infectious Diseases, Singapore, Singapore., Oliver BG; School of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW, Australia.; Woolcock Institute of Medical Research, The University of Sydney, Sydney, NSW, Australia., Wark PAB; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia.; Department of Respiratory and Sleep Medicine, John Hunter Hospital, New Lambton Heights, NSW, Australia., Liu L; School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore, Singapore.; School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, Singapore., Tan NS; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore., Wang LF; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.; Singhealth Duke-NUS Global Health Institute, Singapore, Singapore., Chotirmall SH; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore. schotirmall@ntu.edu.sg.; Department of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore, Singapore. schotirmall@ntu.edu.sg.
Source: Nature communications [Nat Commun] 2022 Dec 10; Vol. 13 (1), pp. 7635. Date of Electronic Publication: 2022 Dec 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: The establishment of COPD organoids to study host-pathogen interaction reveals enhanced viral fitness of SARS-CoV-2 in bronchi.
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  Data: <searchLink fieldCode="AU" term="%22Chan+LLY%22">Chan LLY</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore. louisa.chanly@ntu.edu.sg.<br /><searchLink fieldCode="AU" term="%22Anderson+DE%22">Anderson DE</searchLink>; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Cheng+HS%22">Cheng HS</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Ivan+FX%22">Ivan FX</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Chen+S%22">Chen S</searchLink>; School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Kang+AEZ%22">Kang AEZ</searchLink>; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Foo+R%22">Foo R</searchLink>; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Gamage+AM%22">Gamage AM</searchLink>; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tiew+PY%22">Tiew PY</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Koh+MS%22">Koh MS</searchLink>; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lee+KCH%22">Lee KCH</searchLink>; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Nichol+K%22">Nichol K</searchLink>; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Pathinayake+PS%22">Pathinayake PS</searchLink>; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Chan+YL%22">Chan YL</searchLink>; School of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Yeo+TW%22">Yeo TW</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; National Centre for Infectious Diseases, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Oliver+BG%22">Oliver BG</searchLink>; School of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW, Australia.; Woolcock Institute of Medical Research, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Wark+PAB%22">Wark PAB</searchLink>; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia.; Department of Respiratory and Sleep Medicine, John Hunter Hospital, New Lambton Heights, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore, Singapore.; School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+NS%22">Tan NS</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Wang+LF%22">Wang LF</searchLink>; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.; Singhealth Duke-NUS Global Health Institute, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Chotirmall+SH%22">Chotirmall SH</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore. schotirmall@ntu.edu.sg.; Department of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore, Singapore. schotirmall@ntu.edu.sg.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2022 Dec 10; Vol. 13 (1), pp. 7635. <i>Date of Electronic Publication: </i>2022 Dec 10.
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