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Identification of Genetic Variation Influencing Metformin Response in a Multiancestry Genome-Wide Association Study in the Diabetes Prevention Program (DPP).

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Title: Identification of Genetic Variation Influencing Metformin Response in a Multiancestry Genome-Wide Association Study in the Diabetes Prevention Program (DPP).
Authors: Li JH; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.; Diabetes Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA.; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA.; Department of Medicine, Harvard Medical School, Boston, MA., Perry JA; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD., Jablonski KA; Department of Epidemiology and Biostatistics, George Washington University Biostatistics Center, Washington, DC., Srinivasan S; Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics, University of California, San Francisco, San Francisco, CA., Chen L; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA., Todd JN; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA.; Division of Endocrinology, Department of Pediatrics, Boston Children's Hospital, Boston, MA., Harden M; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA., Mercader JM; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.; Diabetes Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA.; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA.; Department of Medicine, Harvard Medical School, Boston, MA., Pan Q; Department of Epidemiology and Biostatistics, George Washington University Biostatistics Center, Washington, DC., Dawed AY; Division of Population Health and Genomics, Ninewells Hospital and School of Medicine, University of Dundee, Dundee, U.K., Yee SW; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA., Pearson ER; Division of Population Health and Genomics, Ninewells Hospital and School of Medicine, University of Dundee, Dundee, U.K., Giacomini KM; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA., Giri A; Division of Quantitative Sciences, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN., Hung AM; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN., Xiao S; Center for Individualized and Genomic Medicine Research, Department of Internal Medicine, Henry Ford Health System, Detroit, MI., Williams LK; Center for Individualized and Genomic Medicine Research, Department of Internal Medicine, Henry Ford Health System, Detroit, MI., Franks PW; Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Lund University, Malmö, Sweden., Hanson RL; Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, AZ., Kahn SE; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, VA Puget Sound Health Care System and University of Washington, Seattle., Knowler WC; Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, AZ., Pollin TI; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD., Florez JC; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.; Diabetes Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA.; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA.; Department of Medicine, Harvard Medical School, Boston, MA.
Corporate Authors: Diabetes Prevention Program Research Group:
Source: Diabetes [Diabetes] 2023 Aug 01; Vol. 72 (8), pp. 1161-1172.
Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Identification of Genetic Variation Influencing Metformin Response in a Multiancestry Genome-Wide Association Study in the Diabetes Prevention Program (DPP).
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  Data: <searchLink fieldCode="AU" term="%22Li+JH%22">Li JH</searchLink>; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.; Diabetes Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA.; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA.; Department of Medicine, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Perry+JA%22">Perry JA</searchLink>; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Jablonski+KA%22">Jablonski KA</searchLink>; Department of Epidemiology and Biostatistics, George Washington University Biostatistics Center, Washington, DC.<br /><searchLink fieldCode="AU" term="%22Srinivasan+S%22">Srinivasan S</searchLink>; Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics, University of California, San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Chen+L%22">Chen L</searchLink>; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Todd+JN%22">Todd JN</searchLink>; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA.; Division of Endocrinology, Department of Pediatrics, Boston Children's Hospital, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Harden+M%22">Harden M</searchLink>; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Mercader+JM%22">Mercader JM</searchLink>; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.; Diabetes Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA.; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA.; 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Division of Quantitative Sciences, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Hung+AM%22">Hung AM</searchLink>; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Xiao+S%22">Xiao S</searchLink>; Center for Individualized and Genomic Medicine Research, Department of Internal Medicine, Henry Ford Health System, Detroit, MI.<br /><searchLink fieldCode="AU" term="%22Williams+LK%22">Williams LK</searchLink>; Center for Individualized and Genomic Medicine Research, Department of Internal Medicine, Henry Ford Health System, Detroit, MI.<br /><searchLink fieldCode="AU" term="%22Franks+PW%22">Franks PW</searchLink>; Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Lund University, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Hanson+RL%22">Hanson RL</searchLink>; 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Department of Medicine, Harvard Medical School, Boston, MA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Diabetes+Association%22">American Diabetes Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0372763 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1939-327X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200121797%22">00121797 </searchLink><i>NLM ISO Abbreviation: </i>Diabetes <i>Subsets: </i>MEDLINE
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        Value: 10.2337/db22-0702
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