Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo.
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| Title: | Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo. |
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| Authors: | Bachmann M; Department of Biology, University of Padova, Padova, Italy. magdalena.bachmann@unipd.it., Rossa A; Department of Chemical Sciences, University of Padova, Padova, Italy., Varanita T; Department of Biology, University of Padova, Padova, Italy., Fioretti B; Department of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy., Biasutto L; CNR Institute of Neuroscience, Padova, Italy., Milenkovic S; CNR Institute of Materials, Cagliari, Italy., Checchetto V; Department of Biology, University of Padova, Padova, Italy., Peruzzo R; Department of Biology, University of Padova, Padova, Italy., Ahmad SA; Department of Surgery, University of Cincinnati, Cincinnati, USA., Patel SH; Department of Surgery, University of Cincinnati, Cincinnati, USA., Lukowski R; Department of Pharmacology, Toxicology and Clinical Pharmacy, University of Tübingen, Tübingen, Germany., Edwards MJ; Department of Surgery, University of Cincinnati, Cincinnati, USA., Ceccarelli M; CNR Institute of Materials, Cagliari, Italy.; Department of Physics, University of Cagliari, Monserrato, Italy., Gulbins E; Department of Molecular Biology, University of Duisburg-Essen, Essen, Germany., Zoratti M; CNR Institute of Neuroscience, Padova, Italy., Mattarei A; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy. andrea.mattarei@unipd.it., Szabo I; Department of Biology, University of Padova, Padova, Italy. ildiko.szabo@unipd.it. |
| Source: | Cell death & disease [Cell Death Dis] 2022 Dec 20; Vol. 13 (12), pp. 1055. Date of Electronic Publication: 2022 Dec 20. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-4889 |
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| DOI: | 10.1038/s41419-022-05463-8 |
