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Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo.

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Title: Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo.
Authors: Bachmann M; Department of Biology, University of Padova, Padova, Italy. magdalena.bachmann@unipd.it., Rossa A; Department of Chemical Sciences, University of Padova, Padova, Italy., Varanita T; Department of Biology, University of Padova, Padova, Italy., Fioretti B; Department of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy., Biasutto L; CNR Institute of Neuroscience, Padova, Italy., Milenkovic S; CNR Institute of Materials, Cagliari, Italy., Checchetto V; Department of Biology, University of Padova, Padova, Italy., Peruzzo R; Department of Biology, University of Padova, Padova, Italy., Ahmad SA; Department of Surgery, University of Cincinnati, Cincinnati, USA., Patel SH; Department of Surgery, University of Cincinnati, Cincinnati, USA., Lukowski R; Department of Pharmacology, Toxicology and Clinical Pharmacy, University of Tübingen, Tübingen, Germany., Edwards MJ; Department of Surgery, University of Cincinnati, Cincinnati, USA., Ceccarelli M; CNR Institute of Materials, Cagliari, Italy.; Department of Physics, University of Cagliari, Monserrato, Italy., Gulbins E; Department of Molecular Biology, University of Duisburg-Essen, Essen, Germany., Zoratti M; CNR Institute of Neuroscience, Padova, Italy., Mattarei A; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy. andrea.mattarei@unipd.it., Szabo I; Department of Biology, University of Padova, Padova, Italy. ildiko.szabo@unipd.it.
Source: Cell death & disease [Cell Death Dis] 2022 Dec 20; Vol. 13 (12), pp. 1055. Date of Electronic Publication: 2022 Dec 20.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo.
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  Data: <searchLink fieldCode="AU" term="%22Bachmann+M%22">Bachmann M</searchLink>; Department of Biology, University of Padova, Padova, Italy. magdalena.bachmann@unipd.it.<br /><searchLink fieldCode="AU" term="%22Rossa+A%22">Rossa A</searchLink>; Department of Chemical Sciences, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Varanita+T%22">Varanita T</searchLink>; Department of Biology, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Fioretti+B%22">Fioretti B</searchLink>; Department of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Biasutto+L%22">Biasutto L</searchLink>; CNR Institute of Neuroscience, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Milenkovic+S%22">Milenkovic S</searchLink>; CNR Institute of Materials, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Checchetto+V%22">Checchetto V</searchLink>; Department of Biology, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Peruzzo+R%22">Peruzzo R</searchLink>; Department of Biology, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Ahmad+SA%22">Ahmad SA</searchLink>; Department of Surgery, University of Cincinnati, Cincinnati, USA.<br /><searchLink fieldCode="AU" term="%22Patel+SH%22">Patel SH</searchLink>; Department of Surgery, University of Cincinnati, Cincinnati, USA.<br /><searchLink fieldCode="AU" term="%22Lukowski+R%22">Lukowski R</searchLink>; Department of Pharmacology, Toxicology and Clinical Pharmacy, University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Edwards+MJ%22">Edwards MJ</searchLink>; Department of Surgery, University of Cincinnati, Cincinnati, USA.<br /><searchLink fieldCode="AU" term="%22Ceccarelli+M%22">Ceccarelli M</searchLink>; CNR Institute of Materials, Cagliari, Italy.; Department of Physics, University of Cagliari, Monserrato, Italy.<br /><searchLink fieldCode="AU" term="%22Gulbins+E%22">Gulbins E</searchLink>; Department of Molecular Biology, University of Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Zoratti+M%22">Zoratti M</searchLink>; CNR Institute of Neuroscience, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Mattarei+A%22">Mattarei A</searchLink>; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy. andrea.mattarei@unipd.it.<br /><searchLink fieldCode="AU" term="%22Szabo+I%22">Szabo I</searchLink>; Department of Biology, University of Padova, Padova, Italy. ildiko.szabo@unipd.it.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2022 Dec 20; Vol. 13 (12), pp. 1055. <i>Date of Electronic Publication: </i>2022 Dec 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101524092 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-4889 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Death Dis <i>Subsets: </i>MEDLINE
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