Implantable niche with local immunosuppression for islet allotransplantation achieves type 1 diabetes reversal in rats.

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Title: Implantable niche with local immunosuppression for islet allotransplantation achieves type 1 diabetes reversal in rats.
Authors: Paez-Mayorga J; Department of Nanomedicine, Houston Methodist Research Institute, Houston, TX, USA.; School of Medicine and Health Sciences, Tecnologico de Monterrey, Monterrey, NL, Mexico., Campa-Carranza JN; Department of Nanomedicine, Houston Methodist Research Institute, Houston, TX, USA.; School of Medicine and Health Sciences, Tecnologico de Monterrey, Monterrey, NL, Mexico., Capuani S; Department of Nanomedicine, Houston Methodist Research Institute, Houston, TX, USA.; University of the Chinese Academy of Sciences (UCAS), Shijingshan, Beijing, China., Hernandez N; Department of Nanomedicine, Houston Methodist Research Institute, Houston, TX, USA., Liu HC; Department of Nanomedicine, Houston Methodist Research Institute, Houston, TX, USA., Chua CYX; Department of Nanomedicine, Houston Methodist Research Institute, Houston, TX, USA., Pons-Faudoa FP; Department of Nanomedicine, Houston Methodist Research Institute, Houston, TX, USA., Malgir G; Department of Nanomedicine, Houston Methodist Research Institute, Houston, TX, USA., Alvarez B; Department of Nanomedicine, Houston Methodist Research Institute, Houston, TX, USA.; School of Medicine and Health Sciences, Tecnologico de Monterrey, Monterrey, NL, Mexico., Niles JA; Center for Tissue Engineering, Houston Methodist Research Institute, Houston, TX, USA., Argueta LB; Center for Tissue Engineering, Houston Methodist Research Institute, Houston, TX, USA., Shelton KA; Department of Comparative Medicine, Michael E. Keeling Center for Comparative Medicine and Research, MD Anderson Cancer Center, Bastrop, TX, USA., Kezar S; Department of Comparative Medicine, Michael E. Keeling Center for Comparative Medicine and Research, MD Anderson Cancer Center, Bastrop, TX, USA., Nehete PN; Department of Comparative Medicine, Michael E. Keeling Center for Comparative Medicine and Research, MD Anderson Cancer Center, Bastrop, TX, USA.; The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX, USA., Berman DM; Diabetes Research Institute, University of Miami, Miami, FL, USA.; Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA., Willman MA; Diabetes Research Institute, University of Miami, Miami, FL, USA., Li XC; Department of Surgery, Houston Methodist Hospital, Houston, TX, USA.; Immunobiology and Transplant Science Center, Houston Methodist Hospital, Houston, TX, USA., Ricordi C; Diabetes Research Institute, University of Miami, Miami, FL, USA., Nichols JE; Center for Tissue Engineering, Houston Methodist Research Institute, Houston, TX, USA.; Department of Surgery, Houston Methodist Hospital, Houston, TX, USA., Gaber AO; Department of Surgery, Houston Methodist Hospital, Houston, TX, USA., Kenyon NS; Diabetes Research Institute, University of Miami, Miami, FL, USA.; Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.; Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, USA.; Department of Biomedical Engineering, University of Miami, Miami, FL, USA.; Department of Biochemistry and Molecular Biology, University of Miami, Miami, FL, USA., Grattoni A; Department of Nanomedicine, Houston Methodist Research Institute, Houston, TX, USA. agrattoni@houstonmethodist.org.; Department of Surgery, Houston Methodist Hospital, Houston, TX, USA. agrattoni@houstonmethodist.org.; Department of Biochemistry and Molecular Biology, University of Miami, Miami, FL, USA. agrattoni@houstonmethodist.org.; Department of Radiation Oncology, Houston Methodist Hospital, Houston, TX, USA. agrattoni@houstonmethodist.org.
Source: Nature communications [Nat Commun] 2022 Dec 26; Vol. 13 (1), pp. 7951. Date of Electronic Publication: 2022 Dec 26.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-022-35629-z