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The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis.

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Title: The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis.
Authors: Han L; Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, 171 Ashley Ave, Charleston, SC, 29425, USA., Wu Y; Department of Microbiology and Immunology, Hollings Cancer Center, Medical University of South Carolina, 171 Ashley Ave, Charleston, SC, 29425, USA.; Medical College of Wisconsin Cancer Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA., Fang K; Division of Biostatistics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Medical College of Wisconsin Cancer Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA., Sweeney S; Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, 171 Ashley Ave, Charleston, SC, 29425, USA., Roesner UK; Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, 171 Ashley Ave, Charleston, SC, 29425, USA., Parrish M; Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, 171 Ashley Ave, Charleston, SC, 29425, USA., Patel K; Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, 171 Ashley Ave, Charleston, SC, 29425, USA., Walter T; Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, 171 Ashley Ave, Charleston, SC, 29425, USA., Piermattei J; Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, 171 Ashley Ave, Charleston, SC, 29425, USA., Trimboli A; Medical College of Wisconsin Cancer Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Department of Biochemistry, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA., Lefler J; Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, 171 Ashley Ave, Charleston, SC, 29425, USA., Timmers CD; Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, 171 Ashley Ave, Charleston, SC, 29425, USA., Yu XZ; Department of Microbiology and Immunology, Hollings Cancer Center, Medical University of South Carolina, 171 Ashley Ave, Charleston, SC, 29425, USA.; Medical College of Wisconsin Cancer Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA., Jin VX; Division of Biostatistics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Medical College of Wisconsin Cancer Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA., Zimmermann MT; Medical College of Wisconsin Cancer Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Department of Biochemistry, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Clinical and Translational Sciences Institute, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA., Mathison AJ; Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Department of Surgery, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA., Urrutia R; Medical College of Wisconsin Cancer Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Department of Biochemistry, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.; Department of Surgery, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA., Ostrowski MC; Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, 171 Ashley Ave, Charleston, SC, 29425, USA. ostrowsk@musc.edu., Leone G; Medical College of Wisconsin Cancer Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA. gleone@mcw.edu.; Department of Biochemistry, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA. gleone@mcw.edu.
Source: Nature communications [Nat Commun] 2023 Jan 03; Vol. 14 (1), pp. 1. Date of Electronic Publication: 2023 Jan 03.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-022-34464-6