Identifying new biomarkers of aggressive Group 3 and SHH medulloblastoma using 3D hydrogel models, single cell RNA sequencing and 3D OrbiSIMS imaging.
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| Title: | Identifying new biomarkers of aggressive Group 3 and SHH medulloblastoma using 3D hydrogel models, single cell RNA sequencing and 3D OrbiSIMS imaging. |
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| Authors: | Linke F; Children's Brain Tumour Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Johnson JEC; Children's Brain Tumour Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Kern S; School of Pharmacy, University of Nottingham, Nottingham, UK., Bennett CD; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.; Birmingham Children's Hospital, Birmingham, UK., Lourdusamy A; Children's Brain Tumour Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Lea D; Digital Research Service, University of Nottingham, Nottingham, UK., Clifford SC; Wolfson Childhood Cancer Research Centre, Translational & Clinical Research Institute, Newcastle University Centre for Cancer, Newcastle Upon Tyne, NE1 7RU, UK., Merry CLR; School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Stolnik S; School of Pharmacy, University of Nottingham, Nottingham, UK., Alexander MR; School of Pharmacy, University of Nottingham, Nottingham, UK., Peet AC; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.; Birmingham Children's Hospital, Birmingham, UK., Scurr DJ; School of Pharmacy, University of Nottingham, Nottingham, UK., Griffiths RL; School of Pharmacy, University of Nottingham, Nottingham, UK., Grabowska AM; School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Kerr ID; School of Life Sciences, University of Nottingham, Nottingham, UK., Coyle B; Children's Brain Tumour Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK. beth.coyle@nottingham.ac.uk. |
| Source: | Acta neuropathologica communications [Acta Neuropathol Commun] 2023 Jan 11; Vol. 11 (1), pp. 6. Date of Electronic Publication: 2023 Jan 11. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960 (Electronic) Linking ISSN: 20515960 NLM ISO Abbreviation: Acta Neuropathol Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2051-5960 |
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| DOI: | 10.1186/s40478-022-01496-4 |
