Disruption of DDX53 coding sequence has limited impact on iPSC-derived human NGN2 neurons.

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Title: Disruption of DDX53 coding sequence has limited impact on iPSC-derived human NGN2 neurons.
Authors: Faheem M; Genetics & Genome Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON, Canada., Deneault E; Centre for Oncology, Radiopharmaceuticals and Research; Biologic and Radiopharmaceutical Drugs Directorate, Health Products and Food Branch, Health Canada, Ottawa, ON, Canada., Alexandrova R; Genetics & Genome Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON, Canada., Rodrigues DC; Developmental & Stem Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada., Pellecchia G; Genetics & Genome Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON, Canada., Shum C; Genetics & Genome Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON, Canada., Zarrei M; Genetics & Genome Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON, Canada., Piekna A; Developmental & Stem Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada., Wei W; Developmental & Stem Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada., Howe JL; Genetics & Genome Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON, Canada., Thiruvahindrapuram B; Genetics & Genome Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON, Canada., Lamoureux S; Genetics & Genome Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON, Canada., Ross PJ; Developmental & Stem Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; Department of Biology, University of Prince Edward Island, Charlottetown, PE, Canada., Bradley CA; Genetics & Genome Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON, Canada.; Neurosciences & Mental Health Program, Hospital for Sick Children, Toronto, ON, Canada., Ellis J; Developmental & Stem Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Scherer SW; Genetics & Genome Biology Program, Hospital for Sick Children, Toronto, ON, Canada. stephen.scherer@sickkids.ca.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON, Canada. stephen.scherer@sickkids.ca.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada. stephen.scherer@sickkids.ca.; McLaughlin Centre, University of Toronto, Toronto, ON, Canada. stephen.scherer@sickkids.ca.
Source: BMC medical genomics [BMC Med Genomics] 2023 Jan 12; Vol. 16 (1), pp. 5. Date of Electronic Publication: 2023 Jan 12.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101319628 Publication Model: Electronic Cited Medium: Internet ISSN: 1755-8794 (Electronic) Linking ISSN: 17558794 NLM ISO Abbreviation: BMC Med Genomics Subsets: MEDLINE
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  Data: Disruption of DDX53 coding sequence has limited impact on iPSC-derived human NGN2 neurons.
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  Data: <searchLink fieldCode="AU" term="%22Faheem+M%22">Faheem M</searchLink>; Genetics & Genome Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Deneault+E%22">Deneault E</searchLink>; Centre for Oncology, Radiopharmaceuticals and Research; Biologic and Radiopharmaceutical Drugs Directorate, Health Products and Food Branch, Health Canada, Ottawa, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Alexandrova+R%22">Alexandrova R</searchLink>; Genetics & Genome Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Rodrigues+DC%22">Rodrigues DC</searchLink>; Developmental & Stem Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Pellecchia+G%22">Pellecchia G</searchLink>; Genetics & Genome Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Shum+C%22">Shum C</searchLink>; Genetics & Genome Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Zarrei+M%22">Zarrei M</searchLink>; Genetics & Genome Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Piekna+A%22">Piekna A</searchLink>; Developmental & Stem Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Wei+W%22">Wei W</searchLink>; Developmental & Stem Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Howe+JL%22">Howe JL</searchLink>; Genetics & Genome Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Thiruvahindrapuram+B%22">Thiruvahindrapuram B</searchLink>; Genetics & Genome Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Lamoureux+S%22">Lamoureux S</searchLink>; Genetics & Genome Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Ross+PJ%22">Ross PJ</searchLink>; Developmental & Stem Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; Department of Biology, University of Prince Edward Island, Charlottetown, PE, Canada.<br /><searchLink fieldCode="AU" term="%22Bradley+CA%22">Bradley CA</searchLink>; Genetics & Genome Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON, Canada.; Neurosciences & Mental Health Program, Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Ellis+J%22">Ellis J</searchLink>; Developmental & Stem Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Scherer+SW%22">Scherer SW</searchLink>; Genetics & Genome Biology Program, Hospital for Sick Children, Toronto, ON, Canada. stephen.scherer@sickkids.ca.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON, Canada. stephen.scherer@sickkids.ca.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada. stephen.scherer@sickkids.ca.; McLaughlin Centre, University of Toronto, Toronto, ON, Canada. stephen.scherer@sickkids.ca.
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  Data: <searchLink fieldCode="JN" term="%22101319628%22">BMC medical genomics</searchLink> [BMC Med Genomics] 2023 Jan 12; Vol. 16 (1), pp. 5. <i>Date of Electronic Publication: </i>2023 Jan 12.
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        Value: 10.1186/s12920-022-01425-3
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