Discovery of Paltusotine (CRN00808), a Potent, Selective, and Orally Bioavailable Non-peptide SST2 Agonist.
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| Title: | Discovery of Paltusotine (CRN00808), a Potent, Selective, and Orally Bioavailable Non-peptide SST2 Agonist. |
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| Authors: | Zhao J; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, Building #2, San Diego, California 92121, United States., Wang S; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, Building #2, San Diego, California 92121, United States., Markison S; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, Building #2, San Diego, California 92121, United States., Kim SH; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, Building #2, San Diego, California 92121, United States., Han S; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, Building #2, San Diego, California 92121, United States., Chen M; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, Building #2, San Diego, California 92121, United States., Kusnetzow AK; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, Building #2, San Diego, California 92121, United States., Rico-Bautista E; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, Building #2, San Diego, California 92121, United States., Johns M; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, Building #2, San Diego, California 92121, United States., Luo R; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, Building #2, San Diego, California 92121, United States., Struthers RS; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, Building #2, San Diego, California 92121, United States., Madan A; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, Building #2, San Diego, California 92121, United States., Zhu Y; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, Building #2, San Diego, California 92121, United States., Betz SF; Crinetics Pharmaceuticals, Inc., 10222 Barnes Canyon Road, Building #2, San Diego, California 92121, United States. |
| Source: | ACS medicinal chemistry letters [ACS Med Chem Lett] 2022 Dec 10; Vol. 14 (1), pp. 66-74. Date of Electronic Publication: 2022 Dec 10 (Print Publication: 2023). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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