SGK1 inhibition induces fetal hemoglobin expression and delays polymerization in sickle erythroid cells.
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| Title: | SGK1 inhibition induces fetal hemoglobin expression and delays polymerization in sickle erythroid cells. |
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| Authors: | Hara Y; Immunology and Inflammation, Sanofi, Cambridge, MA.; Rare Blood Disorders, Sanofi, Waltham, MA., Lemgart VT; Tidal Therapeutics, Cambridge, MA., Halland N; Integrated Drug Discovery, Sanofi, Frankfurt, Germany., Mahdaviani K; Sickle Cell Center of Excellence, Boston University Medical Center, Boston, MA., Ribeil JA; Sickle Cell Center of Excellence, Boston University Medical Center, Boston, MA., Lessard S; Rare Blood Disorders, Sanofi, Waltham, MA.; Precision Medicine and Computational Biology, Sanofi, Framingham, MA., Hicks A; Immunology and Inflammation, Sanofi, Cambridge, MA.; Rare Blood Disorders, Sanofi, Waltham, MA., Light DR; Rare Blood Disorders, Sanofi, Waltham, MA. |
| Source: | Blood advances [Blood Adv] 2023 Jun 13; Vol. 7 (11), pp. 2317-2323. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 2473-9537 |
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| DOI: | 10.1182/bloodadvances.2022008710 |
