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SGK1 inhibition induces fetal hemoglobin expression and delays polymerization in sickle erythroid cells.

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Title: SGK1 inhibition induces fetal hemoglobin expression and delays polymerization in sickle erythroid cells.
Authors: Hara Y; Immunology and Inflammation, Sanofi, Cambridge, MA.; Rare Blood Disorders, Sanofi, Waltham, MA., Lemgart VT; Tidal Therapeutics, Cambridge, MA., Halland N; Integrated Drug Discovery, Sanofi, Frankfurt, Germany., Mahdaviani K; Sickle Cell Center of Excellence, Boston University Medical Center, Boston, MA., Ribeil JA; Sickle Cell Center of Excellence, Boston University Medical Center, Boston, MA., Lessard S; Rare Blood Disorders, Sanofi, Waltham, MA.; Precision Medicine and Computational Biology, Sanofi, Framingham, MA., Hicks A; Immunology and Inflammation, Sanofi, Cambridge, MA.; Rare Blood Disorders, Sanofi, Waltham, MA., Light DR; Rare Blood Disorders, Sanofi, Waltham, MA.
Source: Blood advances [Blood Adv] 2023 Jun 13; Vol. 7 (11), pp. 2317-2323.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 36696461
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PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: SGK1 inhibition induces fetal hemoglobin expression and delays polymerization in sickle erythroid cells.
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  Data: <searchLink fieldCode="AU" term="%22Hara+Y%22">Hara Y</searchLink>; Immunology and Inflammation, Sanofi, Cambridge, MA.; Rare Blood Disorders, Sanofi, Waltham, MA.<br /><searchLink fieldCode="AU" term="%22Lemgart+VT%22">Lemgart VT</searchLink>; Tidal Therapeutics, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Halland+N%22">Halland N</searchLink>; Integrated Drug Discovery, Sanofi, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Mahdaviani+K%22">Mahdaviani K</searchLink>; Sickle Cell Center of Excellence, Boston University Medical Center, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Ribeil+JA%22">Ribeil JA</searchLink>; Sickle Cell Center of Excellence, Boston University Medical Center, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Lessard+S%22">Lessard S</searchLink>; Rare Blood Disorders, Sanofi, Waltham, MA.; Precision Medicine and Computational Biology, Sanofi, Framingham, MA.<br /><searchLink fieldCode="AU" term="%22Hicks+A%22">Hicks A</searchLink>; Immunology and Inflammation, Sanofi, Cambridge, MA.; Rare Blood Disorders, Sanofi, Waltham, MA.<br /><searchLink fieldCode="AU" term="%22Light+DR%22">Light DR</searchLink>; Rare Blood Disorders, Sanofi, Waltham, MA.
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  Data: <searchLink fieldCode="JN" term="%22101698425%22">Blood advances</searchLink> [Blood Adv] 2023 Jun 13; Vol. 7 (11), pp. 2317-2323.
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  Data: Journal Article; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+of+Hematology%22">American Society of Hematology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101698425 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2473-9537 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224739529%22">24739529 </searchLink><i>NLM ISO Abbreviation: </i>Blood Adv <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1182/bloodadvances.2022008710
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      – Code: eng
        Text: English
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        StartPage: 2317
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      – TitleFull: SGK1 inhibition induces fetal hemoglobin expression and delays polymerization in sickle erythroid cells.
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            NameFull: Hara Y
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            – D: 13
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              Text: 2023 Jun 13
              Type: published
              Y: 2023
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              Value: 11
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