Defective excitation-contraction coupling and mitochondrial respiration precede mitochondrial Ca2+ accumulation in spinobulbar muscular atrophy skeletal muscle.
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| Title: | Defective excitation-contraction coupling and mitochondrial respiration precede mitochondrial Ca2+ accumulation in spinobulbar muscular atrophy skeletal muscle. |
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| Authors: | Marchioretti C; Department of Biomedical Sciences (DBS), University of Padova, 35131, Padova, Italy.; Veneto Institute of Molecular Medicine (VIMM), Padova, 35100, Italy.; Padova Neuroscience Center (PNC), Padova, 35100, Italy.; Dulbecco Telethon Institute (DTI) at the Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, Italy., Zanetti G; Department of Biomedical Sciences (DBS), University of Padova, 35131, Padova, Italy., Pirazzini M; Department of Biomedical Sciences (DBS), University of Padova, 35131, Padova, Italy.; CIR-Myo, Centro Interdipartimentale di Ricerca di Miologia, University of Padova, 35131, Padova, Italy., Gherardi G; Department of Biomedical Sciences (DBS), University of Padova, 35131, Padova, Italy., Nogara L; Department of Biomedical Sciences (DBS), University of Padova, 35131, Padova, Italy.; Veneto Institute of Molecular Medicine (VIMM), Padova, 35100, Italy., Andreotti R; Department of Biomedical Sciences (DBS), University of Padova, 35131, Padova, Italy.; Veneto Institute of Molecular Medicine (VIMM), Padova, 35100, Italy.; Padova Neuroscience Center (PNC), Padova, 35100, Italy., Martini P; Department of Molecular and Translational Medicine, University of Brescia, 25121, Brescia, Italy., Marcucci L; Department of Biomedical Sciences (DBS), University of Padova, 35131, Padova, Italy., Canato M; Department of Biomedical Sciences (DBS), University of Padova, 35131, Padova, Italy., Nath SR; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA., Zuccaro E; Department of Biomedical Sciences (DBS), University of Padova, 35131, Padova, Italy.; Veneto Institute of Molecular Medicine (VIMM), Padova, 35100, Italy.; Padova Neuroscience Center (PNC), Padova, 35100, Italy., Chivet M; Dulbecco Telethon Institute (DTI) at the Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, Italy., Mammucari C; Department of Biomedical Sciences (DBS), University of Padova, 35131, Padova, Italy.; CIR-Myo, Centro Interdipartimentale di Ricerca di Miologia, University of Padova, 35131, Padova, Italy., Pacifici M; Department of Biomedical Sciences (DBS), University of Padova, 35131, Padova, Italy., Raffaello A; Department of Biomedical Sciences (DBS), University of Padova, 35131, Padova, Italy.; CIR-Myo, Centro Interdipartimentale di Ricerca di Miologia, University of Padova, 35131, Padova, Italy., Rizzuto R; Department of Biomedical Sciences (DBS), University of Padova, 35131, Padova, Italy., Mattarei A; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, 35131, Padova, Italy., Desbats MA; Clinical Genetics Unit, Department of Women and Children's Health, University of Padova, and Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padova, Italy., Salviati L; CIR-Myo, Centro Interdipartimentale di Ricerca di Miologia, University of Padova, 35131, Padova, Italy.; Clinical Genetics Unit, Department of Women and Children's Health, University of Padova, and Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padova, Italy., Megighian A; Department of Biomedical Sciences (DBS), University of Padova, 35131, Padova, Italy.; Padova Neuroscience Center (PNC), Padova, 35100, Italy., Sorarù G; Padova Neuroscience Center (PNC), Padova, 35100, Italy.; Department of Neuroscience (DNS), University of Padova, 35128, Padova, Italy., Pegoraro E; Department of Neuroscience (DNS), University of Padova, 35128, Padova, Italy., Belluzzi E; Orthopedics and Orthopedic Oncology, Department of Surgery, Oncology, and Gastroenterology DiSCOG, University-Hospital of Padova, 35128, Padova, Italy.; Musculoskeletal Pathology and Oncology Laboratory, Department of Surgery, Oncology and Gastroenterology (DiSCOG), University of Padova, 35128, Padova, Italy., Pozzuoli A; Orthopedics and Orthopedic Oncology, Department of Surgery, Oncology, and Gastroenterology DiSCOG, University-Hospital of Padova, 35128, Padova, Italy.; Musculoskeletal Pathology and Oncology Laboratory, Department of Surgery, Oncology and Gastroenterology (DiSCOG), University of Padova, 35128, Padova, Italy., Biz C; Orthopedics and Orthopedic Oncology, Department of Surgery, Oncology, and Gastroenterology DiSCOG, University-Hospital of Padova, 35128, Padova, Italy., Ruggieri P; Orthopedics and Orthopedic Oncology, Department of Surgery, Oncology, and Gastroenterology DiSCOG, University-Hospital of Padova, 35128, Padova, Italy., Romualdi C; Department of Biology, University of Padova, Padova, 35100, Italy., Lieberman AP; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA., Babu GJ; Department of Cell Biology and Molecular Medicine, Rutgers, New Jersey Medical School, Newark, NJ, 07103, USA., Sandri M; Department of Biomedical Sciences (DBS), University of Padova, 35131, Padova, Italy.; Veneto Institute of Molecular Medicine (VIMM), Padova, 35100, Italy., Blaauw B; Department of Biomedical Sciences (DBS), University of Padova, 35131, Padova, Italy.; Veneto Institute of Molecular Medicine (VIMM), Padova, 35100, Italy., Basso M; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, Italy., Pennuto M; Department of Biomedical Sciences (DBS), University of Padova, 35131, Padova, Italy. maria.pennuto@unipd.it.; Veneto Institute of Molecular Medicine (VIMM), Padova, 35100, Italy. maria.pennuto@unipd.it.; Padova Neuroscience Center (PNC), Padova, 35100, Italy. maria.pennuto@unipd.it.; Dulbecco Telethon Institute (DTI) at the Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, Italy. maria.pennuto@unipd.it. |
| Source: | Nature communications [Nat Commun] 2023 Feb 06; Vol. 14 (1), pp. 602. Date of Electronic Publication: 2023 Feb 06. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-023-36185-w |