Design of a stable human acid-β-glucosidase: towards improved Gaucher disease therapy and mutation classification.
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| Title: | Design of a stable human acid-β-glucosidase: towards improved Gaucher disease therapy and mutation classification. |
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| Authors: | Pokorna S; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.; J.Heyrovsky Institute of Physical Chemistry of the Czech Academy of Sciences, Prague, Czech Republic., Khersonsky O; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel., Lipsh-Sokolik R; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel., Goldenzweig A; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel., Nielsen R; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel., Ashani Y; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel., Peleg Y; Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel., Unger T; Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel., Albeck S; Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel., Dym O; Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel., Tirosh A; Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel., Tarayra R; Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot, Israel., Hocquemiller M; Lysogene, Neuilly-sur-Seine, France., Laufer R; Lysogene, Neuilly-sur-Seine, France., Ben-Dor S; Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel., Silman I; Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel., Sussman JL; Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot, Israel., Fleishman SJ; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel., Futerman AH; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel. |
| Source: | The FEBS journal [FEBS J] 2023 Jul; Vol. 290 (13), pp. 3383-3399. Date of Electronic Publication: 2023 Mar 23. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1742-4658 |
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| DOI: | 10.1111/febs.16758 |
