An integrated multiomics analysis of rectal cancer patients identified POU2F3 as a putative druggable target and entinostat as a cytotoxic enhancer of 5-fluorouracil.
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| Title: | An integrated multiomics analysis of rectal cancer patients identified POU2F3 as a putative druggable target and entinostat as a cytotoxic enhancer of 5-fluorouracil. |
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| Authors: | D'Angelo E; General Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy.; LIFELAB Program, Consorzio per la Ricerca Sanitaria-CORIS, Padova, Italy.; NanoInspired biomedicine lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padua, Italy., Pastrello C; Osteoarthritis Research Program, Division of Orthopedic Surgery, Schroeder Arthritis Institute and Data Science Discovery Centre for Chronic Diseases, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada., Biccari A; General Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy.; LIFELAB Program, Consorzio per la Ricerca Sanitaria-CORIS, Padova, Italy., Marangio A; General Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy., Sensi F; NanoInspired biomedicine lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padua, Italy.; Department of Women and Children's Health, University of Padova, Padua, Italy., Crotti S; NanoInspired biomedicine lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padua, Italy., Fassan M; Department of Medicine, University of Padua, Padova, Italy.; Veneto Institute of Oncology-Institute for Hospitalization and Care Scientific, Padova, Italy., Jurisica I; Osteoarthritis Research Program, Division of Orthopedic Surgery, Schroeder Arthritis Institute and Data Science Discovery Centre for Chronic Diseases, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.; Department of Medical Biophysics and Computer Science, and Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada.; Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia., Pucciarelli S; General Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy., Agostini M; General Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy.; LIFELAB Program, Consorzio per la Ricerca Sanitaria-CORIS, Padova, Italy.; NanoInspired biomedicine lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padua, Italy. |
| Source: | International journal of cancer [Int J Cancer] 2023 Jul 15; Vol. 153 (2), pp. 437-449. Date of Electronic Publication: 2023 Mar 23. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0215 (Electronic) Linking ISSN: 00207136 NLM ISO Abbreviation: Int J Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1097-0215 |
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| DOI: | 10.1002/ijc.34478 |
