A cell state specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma.

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Title: A cell state specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma.
Authors: Banu MA; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA., Dovas A; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Argenziano MG; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA., Zhao W; Department of System Biology, Columbia University Irving Medical Center, New York, NY, USA., Grajal HC; Spanish National Center for Cardiovascular Research, Madrid, Spain., Higgins DMO; Department of Neurological Surgery, University of North Carolina School of Medicine, Chapel Hill, NC, USA., Sperring CP; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA., Pereira B; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Ye LF; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Mahajan A; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Humala N; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Furnari JL; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Upadhyayula PS; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA., Zandkarimi F; Department of Biological Sciences and Department of Chemistry, Columbia University, New York, NY, USA., Nguyen TTT; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Wu PB; Department of Neurological Surgery, UCLA Geffen School of Medicine, Los Angeles, CA, USA., Hai L; Sulzberger Columbia Genome Center, Columbia University, New York, NY, USA., Karan C; Sulzberger Columbia Genome Center, Columbia University, New York, NY, USA., Razavilar A; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Siegelin MD; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Kitajewski J; University of Illinois Cancer Center, Department of Physiology and Biophysics, University of Illinois Chicago, Chicago, IL, USA., Bruce JN; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA., Stockwell BR; Department of Biological Sciences and Department of Chemistry, Columbia University, New York, NY, USA., Sims PA; Department of System Biology, Columbia University Irving Medical Center, New York, NY, USA., Canoll PD; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2023 Feb 23. Date of Electronic Publication: 2023 Feb 23.
Publication Type: Preprint; Journal Article
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.1101/2023.02.22.529581