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A cell state specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma.

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Title: A cell state specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma.
Authors: Banu MA; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA., Dovas A; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Argenziano MG; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA., Zhao W; Department of System Biology, Columbia University Irving Medical Center, New York, NY, USA., Grajal HC; Spanish National Center for Cardiovascular Research, Madrid, Spain., Higgins DMO; Department of Neurological Surgery, University of North Carolina School of Medicine, Chapel Hill, NC, USA., Sperring CP; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA., Pereira B; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Ye LF; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Mahajan A; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Humala N; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Furnari JL; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Upadhyayula PS; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA., Zandkarimi F; Department of Biological Sciences and Department of Chemistry, Columbia University, New York, NY, USA., Nguyen TTT; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Wu PB; Department of Neurological Surgery, UCLA Geffen School of Medicine, Los Angeles, CA, USA., Hai L; Sulzberger Columbia Genome Center, Columbia University, New York, NY, USA., Karan C; Sulzberger Columbia Genome Center, Columbia University, New York, NY, USA., Razavilar A; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Siegelin MD; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Kitajewski J; University of Illinois Cancer Center, Department of Physiology and Biophysics, University of Illinois Chicago, Chicago, IL, USA., Bruce JN; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA., Stockwell BR; Department of Biological Sciences and Department of Chemistry, Columbia University, New York, NY, USA., Sims PA; Department of System Biology, Columbia University Irving Medical Center, New York, NY, USA., Canoll PD; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2023 Feb 23. Date of Electronic Publication: 2023 Feb 23.
Publication Type: Preprint; Journal Article
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: A cell state specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma.
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  Data: <searchLink fieldCode="AU" term="%22Banu+MA%22">Banu MA</searchLink>; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Dovas+A%22">Dovas A</searchLink>; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Argenziano+MG%22">Argenziano MG</searchLink>; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+W%22">Zhao W</searchLink>; Department of System Biology, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Grajal+HC%22">Grajal HC</searchLink>; Spanish National Center for Cardiovascular Research, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Higgins+DMO%22">Higgins DMO</searchLink>; Department of Neurological Surgery, University of North Carolina School of Medicine, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Sperring+CP%22">Sperring CP</searchLink>; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Pereira+B%22">Pereira B</searchLink>; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ye+LF%22">Ye LF</searchLink>; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Mahajan+A%22">Mahajan A</searchLink>; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Humala+N%22">Humala N</searchLink>; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Furnari+JL%22">Furnari JL</searchLink>; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Upadhyayula+PS%22">Upadhyayula PS</searchLink>; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Zandkarimi+F%22">Zandkarimi F</searchLink>; Department of Biological Sciences and Department of Chemistry, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+TTT%22">Nguyen TTT</searchLink>; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Wu+PB%22">Wu PB</searchLink>; Department of Neurological Surgery, UCLA Geffen School of Medicine, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hai+L%22">Hai L</searchLink>; Sulzberger Columbia Genome Center, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Karan+C%22">Karan C</searchLink>; Sulzberger Columbia Genome Center, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Razavilar+A%22">Razavilar A</searchLink>; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Siegelin+MD%22">Siegelin MD</searchLink>; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Kitajewski+J%22">Kitajewski J</searchLink>; University of Illinois Cancer Center, Department of Physiology and Biophysics, University of Illinois Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Bruce+JN%22">Bruce JN</searchLink>; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Stockwell+BR%22">Stockwell BR</searchLink>; Department of Biological Sciences and Department of Chemistry, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Sims+PA%22">Sims PA</searchLink>; Department of System Biology, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Canoll+PD%22">Canoll PD</searchLink>; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2023 Feb 23. <i>Date of Electronic Publication: </i>2023 Feb 23.
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