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SOX2 dosage sustains tumor-promoting inflammation to drive disease aggressiveness by modulating the FOSL2/IL6 axis.

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Title: SOX2 dosage sustains tumor-promoting inflammation to drive disease aggressiveness by modulating the FOSL2/IL6 axis.
Authors: Njouendou AJ; Department of Biomedical Sciences, Faculty of Health Sciences, University of Buea, Buea, South West Region, Cameroon.; Phytopharmacy and Drug Discovery Section, The Cameroon Consortium for Translational Cancer Research (CCOTCARE), Douala, Cameroon., Szarvas T; Department of Urology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, 45122, Essen, Germany.; Department of Urology, Semmelweis University, 1082, Budapest, Hungary., Tiofack AAZ; Molecular Parasitology and Entomology Unit (MPEU), Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, West Region, Cameroon.; Early Detection and Biomarker Section, The Cameroon Consortium for Translational Cancer Research (CCOTCARE), Douala, Cameroon., Kenfack RN; Early Detection and Biomarker Section, The Cameroon Consortium for Translational Cancer Research (CCOTCARE), Douala, Cameroon.; Research Unit of Microbiology and Antimicrobial Substances (RUMAS), Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, West Region, Cameroon., Tonouo PD; Early Detection and Biomarker Section, The Cameroon Consortium for Translational Cancer Research (CCOTCARE), Douala, Cameroon.; Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Littoral Region, Cameroon.; Department of Medical Oncology, Douala General Hospital, Douala, Littoral Region, Cameroon., Ananga SN; Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Littoral Region, Cameroon.; Department of Medical Oncology, Douala General Hospital, Douala, Littoral Region, Cameroon.; Epidemiology and Clinical Trial Section, The Cameroon Consortium for Translational Cancer Research (CCOTCARE), Douala, Cameroon., Bell EHMD; Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Littoral Region, Cameroon.; Department of Medical Oncology, Douala General Hospital, Douala, Littoral Region, Cameroon.; Epidemiology and Clinical Trial Section, The Cameroon Consortium for Translational Cancer Research (CCOTCARE), Douala, Cameroon., Simo G; Molecular Parasitology and Entomology Unit (MPEU), Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, West Region, Cameroon.; Directorate of Scientific Affairs, The Cameroon Consortium for Translational Cancer Research (CCOTCARE), Douala, Cameroon., Hoheisel JD; Division of Functional Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany., Siveke JT; Bridge Institute for Experimental Cancer Therapy, West German Cancer Center, University Hospital Essen, Hufeland Str. 55, 45147, Essen, Germany.; Division for Solid Tumor Translational Oncology German Cancer Research Center (DKFZ)West German Cancer Center, The German Consortium for Translational Cancer Research (DKTK), Essen/Düsseldorf Partner, Site University Hospital Essen, Essen, Germany., Lueong SS; Department of Biomedical Sciences, Faculty of Health Sciences, University of Buea, Buea, South West Region, Cameroon. smiths-sengkwawoh.lueong@uk-essen.de.; Molecular Parasitology and Entomology Unit (MPEU), Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, West Region, Cameroon. smiths-sengkwawoh.lueong@uk-essen.de.; Early Detection and Biomarker Section, The Cameroon Consortium for Translational Cancer Research (CCOTCARE), Douala, Cameroon. smiths-sengkwawoh.lueong@uk-essen.de.; Bridge Institute for Experimental Cancer Therapy, West German Cancer Center, University Hospital Essen, Hufeland Str. 55, 45147, Essen, Germany. smiths-sengkwawoh.lueong@uk-essen.de.; Division for Solid Tumor Translational Oncology German Cancer Research Center (DKFZ)West German Cancer Center, The German Consortium for Translational Cancer Research (DKTK), Essen/Düsseldorf Partner, Site University Hospital Essen, Essen, Germany. smiths-sengkwawoh.lueong@uk-essen.de.
Source: Molecular cancer [Mol Cancer] 2023 Mar 17; Vol. 22 (1), pp. 52. Date of Electronic Publication: 2023 Mar 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598 (Electronic) Linking ISSN: 14764598 NLM ISO Abbreviation: Mol Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: SOX2 dosage sustains tumor-promoting inflammation to drive disease aggressiveness by modulating the FOSL2/IL6 axis.
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  Data: <searchLink fieldCode="AU" term="%22Njouendou+AJ%22">Njouendou AJ</searchLink>; Department of Biomedical Sciences, Faculty of Health Sciences, University of Buea, Buea, South West Region, Cameroon.; Phytopharmacy and Drug Discovery Section, The Cameroon Consortium for Translational Cancer Research (CCOTCARE), Douala, Cameroon.<br /><searchLink fieldCode="AU" term="%22Szarvas+T%22">Szarvas T</searchLink>; Department of Urology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, 45122, Essen, Germany.; Department of Urology, Semmelweis University, 1082, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Tiofack+AAZ%22">Tiofack AAZ</searchLink>; Molecular Parasitology and Entomology Unit (MPEU), Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, West Region, Cameroon.; Early Detection and Biomarker Section, The Cameroon Consortium for Translational Cancer Research (CCOTCARE), Douala, Cameroon.<br /><searchLink fieldCode="AU" term="%22Kenfack+RN%22">Kenfack RN</searchLink>; Early Detection and Biomarker Section, The Cameroon Consortium for Translational Cancer Research (CCOTCARE), Douala, Cameroon.; Research Unit of Microbiology and Antimicrobial Substances (RUMAS), Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, West Region, Cameroon.<br /><searchLink fieldCode="AU" term="%22Tonouo+PD%22">Tonouo PD</searchLink>; Early Detection and Biomarker Section, The Cameroon Consortium for Translational Cancer Research (CCOTCARE), Douala, Cameroon.; Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Littoral Region, Cameroon.; Department of Medical Oncology, Douala General Hospital, Douala, Littoral Region, Cameroon.<br /><searchLink fieldCode="AU" term="%22Ananga+SN%22">Ananga SN</searchLink>; Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Littoral Region, Cameroon.; Department of Medical Oncology, Douala General Hospital, Douala, Littoral Region, Cameroon.; Epidemiology and Clinical Trial Section, The Cameroon Consortium for Translational Cancer Research (CCOTCARE), Douala, Cameroon.<br /><searchLink fieldCode="AU" term="%22Bell+EHMD%22">Bell EHMD</searchLink>; Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Littoral Region, Cameroon.; Department of Medical Oncology, Douala General Hospital, Douala, Littoral Region, Cameroon.; Epidemiology and Clinical Trial Section, The Cameroon Consortium for Translational Cancer Research (CCOTCARE), Douala, Cameroon.<br /><searchLink fieldCode="AU" term="%22Simo+G%22">Simo G</searchLink>; Molecular Parasitology and Entomology Unit (MPEU), Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, West Region, Cameroon.; Directorate of Scientific Affairs, The Cameroon Consortium for Translational Cancer Research (CCOTCARE), Douala, Cameroon.<br /><searchLink fieldCode="AU" term="%22Hoheisel+JD%22">Hoheisel JD</searchLink>; Division of Functional Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Siveke+JT%22">Siveke JT</searchLink>; Bridge Institute for Experimental Cancer Therapy, West German Cancer Center, University Hospital Essen, Hufeland Str. 55, 45147, Essen, Germany.; Division for Solid Tumor Translational Oncology German Cancer Research Center (DKFZ)West German Cancer Center, The German Consortium for Translational Cancer Research (DKTK), Essen/Düsseldorf Partner, Site University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Lueong+SS%22">Lueong SS</searchLink>; Department of Biomedical Sciences, Faculty of Health Sciences, University of Buea, Buea, South West Region, Cameroon. smiths-sengkwawoh.lueong@uk-essen.de.; Molecular Parasitology and Entomology Unit (MPEU), Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, West Region, Cameroon. smiths-sengkwawoh.lueong@uk-essen.de.; Early Detection and Biomarker Section, The Cameroon Consortium for Translational Cancer Research (CCOTCARE), Douala, Cameroon. smiths-sengkwawoh.lueong@uk-essen.de.; Bridge Institute for Experimental Cancer Therapy, West German Cancer Center, University Hospital Essen, Hufeland Str. 55, 45147, Essen, Germany. smiths-sengkwawoh.lueong@uk-essen.de.; Division for Solid Tumor Translational Oncology German Cancer Research Center (DKFZ)West German Cancer Center, The German Consortium for Translational Cancer Research (DKTK), Essen/Düsseldorf Partner, Site University Hospital Essen, Essen, Germany. smiths-sengkwawoh.lueong@uk-essen.de.
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  Data: <searchLink fieldCode="JN" term="%22101147698%22">Molecular cancer</searchLink> [Mol Cancer] 2023 Mar 17; Vol. 22 (1), pp. 52. <i>Date of Electronic Publication: </i>2023 Mar 17.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101147698 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-4598 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214764598%22">14764598 </searchLink><i>NLM ISO Abbreviation: </i>Mol Cancer <i>Subsets: </i>MEDLINE
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