High-throughput functional analysis of autism genes in zebrafish identifies convergence in dopaminergic and neuroimmune pathways.

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Title: High-throughput functional analysis of autism genes in zebrafish identifies convergence in dopaminergic and neuroimmune pathways.
Authors: Weinschutz Mendes H; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Neelakantan U; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Liu Y; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510, USA., Fitzpatrick SE; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510, USA; MD-PhD Program, Yale School of Medicine, New Haven, CT 06510, USA., Chen T; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Wu W; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510, USA., Pruitt A; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510, USA., Jin DS; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510, USA; Department of Neurology, Yale School of Medicine, New Haven, CT 06510, USA., Jamadagni P; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Carlson M; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510, USA., Lacadie CM; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT 06510, USA., Enriquez KD; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Li N; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510, USA; SJTU-Yale Joint Center for Biostatistics and Data Science, Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China., Zhao D; Department of Genetics, Yale Center for Genome Analysis, Yale School of Medicine, New Haven, CT 06510, USA., Ijaz S; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Sakai C; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Szi C; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Rooney B; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Ghosh M; Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK., Nwabudike I; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510, USA; MD-PhD Program, Yale School of Medicine, New Haven, CT 06510, USA; Department of Psychiatry, Yale School of Medicine, New Haven, CT 06510, USA., Gorodezky A; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Chowdhury S; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Zaheer M; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., McLaughlin S; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Fernandez JM; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Wu J; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Eilbott JA; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Vander Wyk B; Department of Internal Medicine, Section of Geriatrics, Yale School of Medicine, New Haven, CT 06510, USA., Rihel J; Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK., Papademetris X; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT 06510, USA; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, USA., Wang Z; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510, USA., Hoffman EJ; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA. Electronic address: ellen.hoffman@yale.edu.
Source: Cell reports [Cell Rep] 2023 Mar 28; Vol. 42 (3), pp. 112243. Date of Electronic Publication: 2023 Mar 17.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2211-1247
DOI:10.1016/j.celrep.2023.112243