View in EDS

Uterine leiomyosarcomas harboring MAP2K4 gene amplification are sensitive in vivo to PLX8725, a novel MAP2K4 inhibitor.

Saved in:
Bibliographic Details
Title: Uterine leiomyosarcomas harboring MAP2K4 gene amplification are sensitive in vivo to PLX8725, a novel MAP2K4 inhibitor.
Authors: McNamara B; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America., Harold J; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America., Manavella D; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America., Bellone S; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America., Mutlu L; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America., Hartwich TMP; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America., Zipponi M; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America., Yang-Hartwich Y; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America., Demirkiran C; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America., Verzosa MSZ; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America., Yang K; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America., Choi J; Department of Biomedical Sciences, Korea University College of Medicine, 02841 Seoul, Republic of Korea., Dong W; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, United States of America., Buza N; Department of Pathology, Yale University School of Medicine, New Haven, CT 06510, United States of America., Hui P; Department of Pathology, Yale University School of Medicine, New Haven, CT 06510, United States of America., Altwerger G; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America., Huang GS; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America., Andikyan V; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America., Clark M; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America., Ratner E; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America., Azodi M; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America., Schwartz PE; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America., Burton EA; Plexxikon Inc., South San Francisco, CA 94080, United States of America., Inagaki H; Plexxikon Inc., South San Francisco, CA 94080, United States of America., Albers A; Plexxikon Inc., South San Francisco, CA 94080, United States of America., Zhang C; Plexxikon Inc., South San Francisco, CA 94080, United States of America., Bollag G; Plexxikon Inc., South San Francisco, CA 94080, United States of America., Schlessinger J; Department of Pharmacology, Yale University School of Medicine, CT 06520, United States of America., Santin AD; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America. Electronic address: alessandro.santin@yale.edu.
Source: Gynecologic oncology [Gynecol Oncol] 2023 May; Vol. 172, pp. 65-71. Date of Electronic Publication: 2023 Mar 21.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0365304 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-6859 (Electronic) Linking ISSN: 00908258 NLM ISO Abbreviation: Gynecol Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 36958197
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Uterine leiomyosarcomas harboring MAP2K4 gene amplification are sensitive in vivo to PLX8725, a novel MAP2K4 inhibitor.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22McNamara+B%22">McNamara B</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America.<br /><searchLink fieldCode="AU" term="%22Harold+J%22">Harold J</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America.<br /><searchLink fieldCode="AU" term="%22Manavella+D%22">Manavella D</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America.<br /><searchLink fieldCode="AU" term="%22Bellone+S%22">Bellone S</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America.<br /><searchLink fieldCode="AU" term="%22Mutlu+L%22">Mutlu L</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America.<br /><searchLink fieldCode="AU" term="%22Hartwich+TMP%22">Hartwich TMP</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America.<br /><searchLink fieldCode="AU" term="%22Zipponi+M%22">Zipponi M</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America.<br /><searchLink fieldCode="AU" term="%22Yang-Hartwich+Y%22">Yang-Hartwich Y</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America.<br /><searchLink fieldCode="AU" term="%22Demirkiran+C%22">Demirkiran C</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America.<br /><searchLink fieldCode="AU" term="%22Verzosa+MSZ%22">Verzosa MSZ</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America.<br /><searchLink fieldCode="AU" term="%22Yang+K%22">Yang K</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America.<br /><searchLink fieldCode="AU" term="%22Choi+J%22">Choi J</searchLink>; Department of Biomedical Sciences, Korea University College of Medicine, 02841 Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Dong+W%22">Dong W</searchLink>; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, United States of America.<br /><searchLink fieldCode="AU" term="%22Buza+N%22">Buza N</searchLink>; Department of Pathology, Yale University School of Medicine, New Haven, CT 06510, United States of America.<br /><searchLink fieldCode="AU" term="%22Hui+P%22">Hui P</searchLink>; Department of Pathology, Yale University School of Medicine, New Haven, CT 06510, United States of America.<br /><searchLink fieldCode="AU" term="%22Altwerger+G%22">Altwerger G</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America.<br /><searchLink fieldCode="AU" term="%22Huang+GS%22">Huang GS</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America.<br /><searchLink fieldCode="AU" term="%22Andikyan+V%22">Andikyan V</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America.<br /><searchLink fieldCode="AU" term="%22Clark+M%22">Clark M</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America.<br /><searchLink fieldCode="AU" term="%22Ratner+E%22">Ratner E</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America.<br /><searchLink fieldCode="AU" term="%22Azodi+M%22">Azodi M</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America.<br /><searchLink fieldCode="AU" term="%22Schwartz+PE%22">Schwartz PE</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America.<br /><searchLink fieldCode="AU" term="%22Burton+EA%22">Burton EA</searchLink>; Plexxikon Inc., South San Francisco, CA 94080, United States of America.<br /><searchLink fieldCode="AU" term="%22Inagaki+H%22">Inagaki H</searchLink>; Plexxikon Inc., South San Francisco, CA 94080, United States of America.<br /><searchLink fieldCode="AU" term="%22Albers+A%22">Albers A</searchLink>; Plexxikon Inc., South San Francisco, CA 94080, United States of America.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Plexxikon Inc., South San Francisco, CA 94080, United States of America.<br /><searchLink fieldCode="AU" term="%22Bollag+G%22">Bollag G</searchLink>; Plexxikon Inc., South San Francisco, CA 94080, United States of America.<br /><searchLink fieldCode="AU" term="%22Schlessinger+J%22">Schlessinger J</searchLink>; Department of Pharmacology, Yale University School of Medicine, CT 06520, United States of America.<br /><searchLink fieldCode="AU" term="%22Santin+AD%22">Santin AD</searchLink>; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, United States of America. Electronic address: alessandro.santin@yale.edu.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%220365304%22">Gynecologic oncology</searchLink> [Gynecol Oncol] 2023 May; Vol. 172, pp. 65-71. <i>Date of Electronic Publication: </i>2023 Mar 21.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0365304 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1095-6859 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200908258%22">00908258 </searchLink><i>NLM ISO Abbreviation: </i>Gynecol Oncol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=36958197
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.ygyno.2023.03.009
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 65
    Titles:
      – TitleFull: Uterine leiomyosarcomas harboring MAP2K4 gene amplification are sensitive in vivo to PLX8725, a novel MAP2K4 inhibitor.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: McNamara B
      – PersonEntity:
          Name:
            NameFull: Harold J
      – PersonEntity:
          Name:
            NameFull: Manavella D
      – PersonEntity:
          Name:
            NameFull: Bellone S
      – PersonEntity:
          Name:
            NameFull: Mutlu L
      – PersonEntity:
          Name:
            NameFull: Hartwich TMP
      – PersonEntity:
          Name:
            NameFull: Zipponi M
      – PersonEntity:
          Name:
            NameFull: Yang-Hartwich Y
      – PersonEntity:
          Name:
            NameFull: Demirkiran C
      – PersonEntity:
          Name:
            NameFull: Verzosa MSZ
      – PersonEntity:
          Name:
            NameFull: Yang K
      – PersonEntity:
          Name:
            NameFull: Choi J
      – PersonEntity:
          Name:
            NameFull: Dong W
      – PersonEntity:
          Name:
            NameFull: Buza N
      – PersonEntity:
          Name:
            NameFull: Hui P
      – PersonEntity:
          Name:
            NameFull: Altwerger G
      – PersonEntity:
          Name:
            NameFull: Huang GS
      – PersonEntity:
          Name:
            NameFull: Andikyan V
      – PersonEntity:
          Name:
            NameFull: Clark M
      – PersonEntity:
          Name:
            NameFull: Ratner E
      – PersonEntity:
          Name:
            NameFull: Azodi M
      – PersonEntity:
          Name:
            NameFull: Schwartz PE
      – PersonEntity:
          Name:
            NameFull: Burton EA
      – PersonEntity:
          Name:
            NameFull: Inagaki H
      – PersonEntity:
          Name:
            NameFull: Albers A
      – PersonEntity:
          Name:
            NameFull: Zhang C
      – PersonEntity:
          Name:
            NameFull: Bollag G
      – PersonEntity:
          Name:
            NameFull: Schlessinger J
      – PersonEntity:
          Name:
            NameFull: Santin AD
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 05
              Text: 2023 May
              Type: published
              Y: 2023
          Identifiers:
            – Type: issn-electronic
              Value: 1095-6859
          Numbering:
            – Type: volume
              Value: 172
          Titles:
            – TitleFull: Gynecologic oncology
              Type: main
ResultId 1