Treatment of severe acute necrotizing encephalopathy of childhood with interleukin-6 receptor blockade in the first 24 h as add-on immunotherapy shows favorable long-term outcome at 2 years.

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Title: Treatment of severe acute necrotizing encephalopathy of childhood with interleukin-6 receptor blockade in the first 24 h as add-on immunotherapy shows favorable long-term outcome at 2 years.
Authors: Hosie PH; Department of Neurology, Sydney Children's Hospital, Randwick, Australia., Lim C; Rehab2Kids, Sydney Children's Hospital, Randwick, Australia., Scott TRD; Rehab2Kids, Sydney Children's Hospital, Randwick, Australia; Discipline of Pediatrics and Child Health, School of Clinical Medicine, UNSW Medicine and Health, UNSW Sydney, Australia; Graduate School of Biomedical Engineering, UNSW Sydney, Australia., Cardamone M; Department of Neurology, Sydney Children's Hospital, Randwick, Australia; Discipline of Pediatrics and Child Health, School of Clinical Medicine, UNSW Medicine and Health, UNSW Sydney, Australia., Farrar MA; Department of Neurology, Sydney Children's Hospital, Randwick, Australia; Discipline of Pediatrics and Child Health, School of Clinical Medicine, UNSW Medicine and Health, UNSW Sydney, Australia., Frith C; Department of Immunology and Infectious Diseases, Sydney Children's Hospital, Randwick, Australia., Andrews PI; Department of Neurology, Sydney Children's Hospital, Randwick, Australia., Pinner J; Centre for Clinical Genetics, Sydney Children's Hospital, Randwick, Australia., Pillai S; Department of Neurology, Sydney Children's Hospital, Randwick, Australia; Discipline of Pediatrics and Child Health, School of Clinical Medicine, UNSW Medicine and Health, UNSW Sydney, Australia. Electronic address: sekhar.pillai@health.nsw.gov.au.
Source: Brain & development [Brain Dev] 2023 Aug; Vol. 45 (7), pp. 401-407. Date of Electronic Publication: 2023 Mar 24.
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909235 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7131 (Electronic) Linking ISSN: 03877604 NLM ISO Abbreviation: Brain Dev Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1872-7131
DOI:10.1016/j.braindev.2023.03.002