Early Infiltration of Innate Immune Cells to the Liver Depletes HNF4α and Promotes Extrahepatic Carcinogenesis.

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Title: Early Infiltration of Innate Immune Cells to the Liver Depletes HNF4α and Promotes Extrahepatic Carcinogenesis.
Authors: Goldman O; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Adler LN; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Hajaj E; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Croese T; Department of Brain Science, Weizmann Institute of Science, Rehovot, Israel., Darzi N; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Galai S; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Tishler H; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Ariav Y; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Lavie D; Department of Pathology, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Fellus-Alyagor L; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel., Oren R; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel., Kuznetsov Y; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel., David E; Department of System Immunology, Weizmann Institute of Science, Rehovot, Israel., Jaschek R; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel., Stossel C; Oncology Institute, Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel., Singer O; Life Science Core Facility, Weizmann Institute of Science, Rehovot, Israel., Malitsky S; Life Science Core Facility, Weizmann Institute of Science, Rehovot, Israel., Barak R; Oncology Division, Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel., Seger R; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel., Erez N; Department of Pathology, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Amit I; Department of System Immunology, Weizmann Institute of Science, Rehovot, Israel., Tanay A; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel., Saada A; Department of Genetics, Hadassah Medical Center, Hebrew University and Faculty of Medicine, Jerusalem, Israel., Golan T; Oncology Institute, Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel., Rubinek T; Oncology Division, Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel., Sang Lee J; Department of Precision Medicine, School of Medicine and Department of Artificial Intelligence, Sungkyunkwan University, Suwon, Republic of Korea., Ben-Shachar S; Clalit Research Institute, Innovation Division, Clalit Health Services, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Wolf I; Oncology Division, Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel., Erez A; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Source: Cancer discovery [Cancer Discov] 2023 Jul 07; Vol. 13 (7), pp. 1616-1635.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2159-8290
DOI:10.1158/2159-8290.CD-22-1062