Etiology of oncogenic fusions in 5,190 childhood cancers and its clinical and therapeutic implication.

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Title: Etiology of oncogenic fusions in 5,190 childhood cancers and its clinical and therapeutic implication.
Authors: Liu Y; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Klein J; Department of Cell and Molecular Biology and Center for Advanced Genome Editing, St. Jude Children's Research Hospital, Memphis, TN, USA., Bajpai R; Department of Cell and Molecular Biology and Center for Advanced Genome Editing, St. Jude Children's Research Hospital, Memphis, TN, USA., Dong L; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Tran Q; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Kolekar P; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Smith JL; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Ries RE; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Huang BJ; Department of Pediatrics and Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA., Wang YC; Children's Oncology Group, Monrovia, CA, USA., Alonzo TA; Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USA., Tian L; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Mulder HL; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Shaw TI; Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, FL, USA., Ma J; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Walsh MP; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Song G; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Westover T; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Autry RJ; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Gout AM; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Wheeler DA; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Wan S; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN, USA., Wu G; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN, USA., Yang JJ; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Evans WE; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Loh M; Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute and the Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA, USA., Easton J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Zhang J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Klco JM; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA. Jeffery.Klco@stjude.org., Meshinchi S; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. smeshinc@fredhutch.org., Brown PA; Bristol Myers Squibb, Princeton, NJ, USA. Patrick.Brown@bms.com., Pruett-Miller SM; Department of Cell and Molecular Biology and Center for Advanced Genome Editing, St. Jude Children's Research Hospital, Memphis, TN, USA. Shondra.Miller@stjude.org., Ma X; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA. Xiaotu.Ma@stjude.org.
Source: Nature communications [Nat Commun] 2023 Apr 05; Vol. 14 (1), pp. 1739. Date of Electronic Publication: 2023 Apr 05.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-023-37438-4