Low glucose induced Alzheimer's disease-like biochemical changes in human induced pluripotent stem cell-derived neurons is due to dysregulated O-GlcNAcylation.

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Title: Low glucose induced Alzheimer's disease-like biochemical changes in human induced pluripotent stem cell-derived neurons is due to dysregulated O-GlcNAcylation.
Authors: Huang CW; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA.; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA., Rust NC; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA.; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA., Wu HF; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.; Center for Molecular Medicine, University of Georgia, Athens, Georgia, USA., Yin A; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.; Center for Molecular Medicine, University of Georgia, Athens, Georgia, USA., Zeltner N; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.; Center for Molecular Medicine, University of Georgia, Athens, Georgia, USA., Yin H; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.; Center for Molecular Medicine, University of Georgia, Athens, Georgia, USA., Hart GW; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA.; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2023 Nov; Vol. 19 (11), pp. 4872-4885. Date of Electronic Publication: 2023 Apr 10.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1552-5279
DOI:10.1002/alz.13058