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To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A?

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Title: To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A?
Authors: Zheng Y; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands., Schroeder S; School of Biosciences, University of Kent, Canterbury CT2 7NJ, UK., Kanev GK; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands., Botros SS; Pharmacology Department, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, P.O. Box 30, Giza 12411, Egypt., William S; Parasitology Department, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, P.O. Box 30, Giza 12411, Egypt., Sabra AA; Pharmacology Department, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, P.O. Box 30, Giza 12411, Egypt., Maes L; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium., Caljon G; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium., Gil C; Centro de Investigaciones Biologicas (CIB-CSIC), Ramiro de Maeztu 9, 28040 Madrid, Spain., Martinez A; Centro de Investigaciones Biologicas (CIB-CSIC), Ramiro de Maeztu 9, 28040 Madrid, Spain., Salado IG; Medicinal Chemistry, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium., Augustyns K; Medicinal Chemistry, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium., Edink E; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands., Sijm M; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands., de Heuvel E; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands., de Esch IJP; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands., van der Meer T; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands., Siderius M; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands., Sterk GJ; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands., Brown D; School of Biosciences, University of Kent, Canterbury CT2 7NJ, UK., Leurs R; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.
Source: International journal of molecular sciences [Int J Mol Sci] 2023 Apr 06; Vol. 24 (7). Date of Electronic Publication: 2023 Apr 06.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Zheng+Y%22">Zheng Y</searchLink>; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Schroeder+S%22">Schroeder S</searchLink>; School of Biosciences, University of Kent, Canterbury CT2 7NJ, UK.<br /><searchLink fieldCode="AU" term="%22Kanev+GK%22">Kanev GK</searchLink>; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Botros+SS%22">Botros SS</searchLink>; Pharmacology Department, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, P.O. Box 30, Giza 12411, Egypt.<br /><searchLink fieldCode="AU" term="%22William+S%22">William S</searchLink>; Parasitology Department, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, P.O. Box 30, Giza 12411, Egypt.<br /><searchLink fieldCode="AU" term="%22Sabra+AA%22">Sabra AA</searchLink>; Pharmacology Department, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, P.O. Box 30, Giza 12411, Egypt.<br /><searchLink fieldCode="AU" term="%22Maes+L%22">Maes L</searchLink>; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium.<br /><searchLink fieldCode="AU" term="%22Caljon+G%22">Caljon G</searchLink>; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium.<br /><searchLink fieldCode="AU" term="%22Gil+C%22">Gil C</searchLink>; Centro de Investigaciones Biologicas (CIB-CSIC), Ramiro de Maeztu 9, 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Martinez+A%22">Martinez A</searchLink>; Centro de Investigaciones Biologicas (CIB-CSIC), Ramiro de Maeztu 9, 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Salado+IG%22">Salado IG</searchLink>; Medicinal Chemistry, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Augustyns+K%22">Augustyns K</searchLink>; Medicinal Chemistry, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Edink+E%22">Edink E</searchLink>; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Sijm+M%22">Sijm M</searchLink>; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Heuvel+E%22">de Heuvel E</searchLink>; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Esch+IJP%22">de Esch IJP</searchLink>; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Meer+T%22">van der Meer T</searchLink>; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Siderius+M%22">Siderius M</searchLink>; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Sterk+GJ%22">Sterk GJ</searchLink>; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Brown+D%22">Brown D</searchLink>; School of Biosciences, University of Kent, Canterbury CT2 7NJ, UK.<br /><searchLink fieldCode="AU" term="%22Leurs+R%22">Leurs R</searchLink>; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%22101092791%22">International journal of molecular sciences</searchLink> [Int J Mol Sci] 2023 Apr 06; Vol. 24 (7). <i>Date of Electronic Publication: </i>2023 Apr 06.
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