Oncogenic CDK13 mutations impede nuclear RNA surveillance.
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| Title: | Oncogenic CDK13 mutations impede nuclear RNA surveillance. |
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| Authors: | Insco ML; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA 02115, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA., Abraham BJ; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Dubbury SJ; The David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Kaltheuner IH; Institute of Structural Biology, University of Bonn, 53127 Bonn, Germany., Dust S; Institute of Structural Biology, University of Bonn, 53127 Bonn, Germany., Wu C; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA 02115, USA., Chen KY; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA 02115, USA., Liu D; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA., Bellaousov S; University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA., Cox AM; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA 02115, USA., Martin BJE; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA., Zhang T; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20850, USA., Ludwig CG; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA 02115, USA., Fabo T; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA 02115, USA., Modhurima R; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA 02115, USA., Esgdaille DE; University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA., Henriques T; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA., Brown KM; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20850, USA., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20850, USA., Geyer M; Institute of Structural Biology, University of Bonn, 53127 Bonn, Germany., Adelman K; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA., Sharp PA; The David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Young RA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA., Boutz PL; University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.; Center for RNA Biology, University of Rochester, Rochester, NY 14642, USA.; Center for Biomedical Informatics, University of Rochester, Rochester, NY 14642, USA., Zon LI; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA 02115, USA. |
| Source: | Science (New York, N.Y.) [Science] 2023 Apr 21; Vol. 380 (6642), pp. eabn7625. Date of Electronic Publication: 2023 Apr 21. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1095-9203 |
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| DOI: | 10.1126/science.abn7625 |
