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Synthesis, biological evaluation and mechanistic studies of 4-(1,3-thiazol-2-yl)morpholine-benzimidazole hybrids as a new structural class of antimicrobials.

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Bibliographic Details
Title: Synthesis, biological evaluation and mechanistic studies of 4-(1,3-thiazol-2-yl)morpholine-benzimidazole hybrids as a new structural class of antimicrobials.
Authors: Aaghaz S; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, S.A.S Nagar, Punjab 160062, India., Digwal CS; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad 500037, India., Neshat N; School of Pharmaceutical Education and Research (SPER), Jamia Hamdard, New Delhi 110062, India., Maurya IK; Center of Infectious Diseases, National Institute of Pharmaceutical Education and Research, S.A.S Nagar, Punjab 160062, India., Kumar V; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, S.A.S. Nagar, Punjab 160062, India., Tikoo K; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, S.A.S. Nagar, Punjab 160062, India., Jain R; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, S.A.S Nagar, Punjab 160062, India. Electronic address: rahuljain@niper.ac.in., Kamal A; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad 500037, India; Birla Institute of Technology & Science (BITS), Pilani Hyderabad Campus, Hyderabad, Telangana, 500078, India. Electronic address: ahmedkamal@iict.res.in.
Source: Bioorganic chemistry [Bioorg Chem] 2023 Jul; Vol. 136, pp. 106538. Date of Electronic Publication: 2023 Apr 13.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1090-2120
DOI:10.1016/j.bioorg.2023.106538