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Intracranial injection of natural killer cells engineered with a HER2-targeted chimeric antigen receptor in patients with recurrent glioblastoma.

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Title: Intracranial injection of natural killer cells engineered with a HER2-targeted chimeric antigen receptor in patients with recurrent glioblastoma.
Authors: Burger MC; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany., Forster MT; Department of Neurosurgery, Goethe University Hospital, Frankfurt, Germany., Romanski A; Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt and Red Cross Blood Donation Service Baden-Württemberg-Hessen, Frankfurt, Germany., Straßheimer F; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany., Macas J; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany., Zeiner PS; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany., Steidl E; Institute of Neuroradiology, Goethe University Hospital, Frankfurt, Germany., Herkt S; Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt and Red Cross Blood Donation Service Baden-Württemberg-Hessen, Frankfurt, Germany., Weber KJ; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.; University Cancer Center (UCT), Goethe University Hospital, Frankfurt, Germany., Schupp J; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany., Lun JH; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany., Strecker MI; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany., Wlotzka K; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany., Cakmak P; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany., Opitz C; Institute for Transfusion Medicine, German Red Cross Blood Donation Service North-East and Medical Faculty Carl Gustav Carus, TU Dresden, Dresden, Germany., George R; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; Department of Radiotherapy and Oncology, Goethe University Hospital, Frankfurt, Germany., Mildenberger IC; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany., Nowakowska P; Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt and Red Cross Blood Donation Service Baden-Württemberg-Hessen, Frankfurt, Germany., Zhang C; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany., Röder J; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany., Müller E; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany., Ihrig K; University Cancer Center (UCT), Goethe University Hospital, Frankfurt, Germany., Langen KJ; Research Center Jülich, Institute of Neuroscience and Medicine, Jülich, Germany.; Department of Nuclear Medicine, University Hospital Aachen, Aachen, Germany., Rieger MA; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Medicine II, Hematology/Oncology, Goethe University Hospital, Frankfurt, Germany., Herrmann E; Institute for Biostatistics and Mathematical Modelling, Goethe University, Frankfurt, Germany., Bonig H; Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt and Red Cross Blood Donation Service Baden-Württemberg-Hessen, Frankfurt, Germany., Harter PN; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany., Reiss Y; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany., Hattingen E; Institute of Neuroradiology, Goethe University Hospital, Frankfurt, Germany., Rödel F; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; Department of Radiotherapy and Oncology, Goethe University Hospital, Frankfurt, Germany., Plate KH; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany., Tonn T; Institute for Transfusion Medicine, German Red Cross Blood Donation Service North-East and Medical Faculty Carl Gustav Carus, TU Dresden, Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden, Dresden, Germany., Senft C; Department of Neurosurgery, Goethe University Hospital, Frankfurt, Germany., Steinbach JP; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany., Wels WS; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
Source: Neuro-oncology [Neuro Oncol] 2023 Nov 02; Vol. 25 (11), pp. 2058-2071.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1523-5866
DOI:10.1093/neuonc/noad087