Single-cell transcriptome analysis of xenotransplanted human retinal organoids defines two migratory cell populations of nonretinal origin.

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Title: Single-cell transcriptome analysis of xenotransplanted human retinal organoids defines two migratory cell populations of nonretinal origin.
Authors: Liu YV; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Santiago CP; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Sogunro A; Department of Biology, Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD, USA., Konar GJ; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Hu MW; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., McNally MM; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Lu YC; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Flores-Bellver M; CellSight Ocular Stem Cell and Regeneration Program, Department of Ophthalmology, Sue Anschutz-Rodgers Eye Center, University of Colorado, School of Medicine, Aurora, CO, USA., Aparicio-Domingo S; CellSight Ocular Stem Cell and Regeneration Program, Department of Ophthalmology, Sue Anschutz-Rodgers Eye Center, University of Colorado, School of Medicine, Aurora, CO, USA., Li KV; CellSight Ocular Stem Cell and Regeneration Program, Department of Ophthalmology, Sue Anschutz-Rodgers Eye Center, University of Colorado, School of Medicine, Aurora, CO, USA., Li ZL; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Agakishiev D; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Hadyniak SE; Department of Biology, Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD, USA., Hussey KA; Department of Biology, Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD, USA., Creamer TJ; Institute for Basic Biomedical Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Orzolek LD; Institute for Basic Biomedical Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Teng D; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Canto-Soler MV; CellSight Ocular Stem Cell and Regeneration Program, Department of Ophthalmology, Sue Anschutz-Rodgers Eye Center, University of Colorado, School of Medicine, Aurora, CO, USA., Qian J; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Jiang Z; Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA., Johnston RJ Jr; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Biology, Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD, USA. Electronic address: robertjohnston@jhu.edu., Blackshaw S; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: sethblackshaw@gmail.com., Singh MS; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: singhcorrespauth@gmail.com.
Source: Stem cell reports [Stem Cell Reports] 2023 May 09; Vol. 18 (5), pp. 1138-1154.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101611300 Publication Model: Print Cited Medium: Internet ISSN: 2213-6711 (Electronic) Linking ISSN: 22136711 NLM ISO Abbreviation: Stem Cell Reports Subsets: MEDLINE
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  Data: Single-cell transcriptome analysis of xenotransplanted human retinal organoids defines two migratory cell populations of nonretinal origin.
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  Data: <searchLink fieldCode="AU" term="%22Liu+YV%22">Liu YV</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Santiago+CP%22">Santiago CP</searchLink>; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Sogunro+A%22">Sogunro A</searchLink>; Department of Biology, Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Konar+GJ%22">Konar GJ</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Hu+MW%22">Hu MW</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22McNally+MM%22">McNally MM</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lu+YC%22">Lu YC</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Flores-Bellver+M%22">Flores-Bellver M</searchLink>; CellSight Ocular Stem Cell and Regeneration Program, Department of Ophthalmology, Sue Anschutz-Rodgers Eye Center, University of Colorado, School of Medicine, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Aparicio-Domingo+S%22">Aparicio-Domingo S</searchLink>; CellSight Ocular Stem Cell and Regeneration Program, Department of Ophthalmology, Sue Anschutz-Rodgers Eye Center, University of Colorado, School of Medicine, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Li+KV%22">Li KV</searchLink>; CellSight Ocular Stem Cell and Regeneration Program, Department of Ophthalmology, Sue Anschutz-Rodgers Eye Center, University of Colorado, School of Medicine, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Li+ZL%22">Li ZL</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Agakishiev+D%22">Agakishiev D</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Hadyniak+SE%22">Hadyniak SE</searchLink>; Department of Biology, Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Hussey+KA%22">Hussey KA</searchLink>; Department of Biology, Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Creamer+TJ%22">Creamer TJ</searchLink>; Institute for Basic Biomedical Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Orzolek+LD%22">Orzolek LD</searchLink>; Institute for Basic Biomedical Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Teng+D%22">Teng D</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Canto-Soler+MV%22">Canto-Soler MV</searchLink>; CellSight Ocular Stem Cell and Regeneration Program, Department of Ophthalmology, Sue Anschutz-Rodgers Eye Center, University of Colorado, School of Medicine, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Qian+J%22">Qian J</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+Z%22">Jiang Z</searchLink>; Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Johnston+RJ+Jr%22">Johnston RJ Jr</searchLink>; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Biology, Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD, USA. Electronic address: robertjohnston@jhu.edu.<br /><searchLink fieldCode="AU" term="%22Blackshaw+S%22">Blackshaw S</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: sethblackshaw@gmail.com.<br /><searchLink fieldCode="AU" term="%22Singh+MS%22">Singh MS</searchLink>; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: singhcorrespauth@gmail.com.
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