Outcomes with spinal versus general anesthesia for patients with and without preoperative cognitive impairment: Secondary analysis of a randomized clinical trial.

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Title: Outcomes with spinal versus general anesthesia for patients with and without preoperative cognitive impairment: Secondary analysis of a randomized clinical trial.
Authors: O'Brien K; Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Feng R; Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Sieber F; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA., Marcantonio ER; Department of Medicine, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, Massachusetts, USA., Tierney A; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Magaziner J; Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA., Carson JL; Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA., Dillane D; Department of Anesthesiology and Pain Medicine, University of Alberta, Edmonton, Canada., Sessler DI; Department of Outcomes Research, Cleveland Clinic, Cleveland, Ohio, USA., Menio D; Center for Advocacy for the Rights and Interests of the Elderly, Philadelphia, Pennsylvania, USA., Ayad S; Department of Outcomes Research, Cleveland Clinic, Cleveland, Ohio, USA., Stone T; Department of Orthopaedics, University of British Columbia, Vancouver, Canada., Papp S; Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa, Canada., Schwenk ES; Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania, USA., Marshall M; Department of Anesthesiology, New York University Langone Medical Center, New York, New York, USA., Jaffe JD; Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA., Luke C; Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA., Sharma B; Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington, Massachusetts, USA., Azim S; Department of Anesthesiology, Stony Brook University, Stony Brook, New York, USA., Hymes R; Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church, Virginia, USA., Chin KJ; Department of Anesthesiology and Pain Medicine, University of Toronto, Toronto, Canada., Sheppard R; Department of Anesthesiology, Hartford Hospital, Hartford, Connecticut, USA., Perlman B; Department of Internal Medicine, Peacehealth Medical Group, Springfield, Oregon, USA., Sappenfield J; Department of Anesthesiology, University of Florida College of Medicine, Gainesville, Florida, USA., Hauck E; Department of Anesthesiology, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA., Hoeft MA; Department of Anesthesiology, University of Vermont Larner College of Medicine, Burlington, Vermont, USA., Karlawish J; Department of Internal Medicine, Division of Geriatric Medicine, Perelman School of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Mehta S; Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Donegan DJ; Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Horan A; Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Ellenberg SS; Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Neuman MD; Department of Internal Medicine, Division of Geriatric Medicine, Perelman School of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.; Department of Anesthesiology and Critical Care, Perelman School of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Corporate Authors: REGAIN (Regional versus General Anesthesia for Promoting Independence after Hip Fracture) Investigators
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2023 Sep; Vol. 19 (9), pp. 4008-4019. Date of Electronic Publication: 2023 May 12.
Publication Type: Randomized Controlled Trial; Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't; Pragmatic Clinical Trial
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
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  Data: Outcomes with spinal versus general anesthesia for patients with and without preoperative cognitive impairment: Secondary analysis of a randomized clinical trial.
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Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Magaziner+J%22">Magaziner J</searchLink>; Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Carson+JL%22">Carson JL</searchLink>; Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Dillane+D%22">Dillane D</searchLink>; Department of Anesthesiology and Pain Medicine, University of Alberta, Edmonton, Canada.<br /><searchLink fieldCode="AU" term="%22Sessler+DI%22">Sessler DI</searchLink>; Department of Outcomes Research, Cleveland Clinic, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Menio+D%22">Menio D</searchLink>; Center for Advocacy for the Rights and Interests of the Elderly, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Ayad+S%22">Ayad S</searchLink>; 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Department of Anesthesiology, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Hauck+E%22">Hauck E</searchLink>; Department of Anesthesiology, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Hoeft+MA%22">Hoeft MA</searchLink>; Department of Anesthesiology, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.<br /><searchLink fieldCode="AU" term="%22Karlawish+J%22">Karlawish J</searchLink>; Department of Internal Medicine, Division of Geriatric Medicine, Perelman School of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Mehta+S%22">Mehta S</searchLink>; Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Donegan+DJ%22">Donegan DJ</searchLink>; Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Horan+A%22">Horan A</searchLink>; Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Ellenberg+SS%22">Ellenberg SS</searchLink>; Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Neuman+MD%22">Neuman MD</searchLink>; Department of Internal Medicine, Division of Geriatric Medicine, Perelman School of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.; Department of Anesthesiology and Critical Care, Perelman School of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
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  Data: <searchLink fieldCode="JN" term="%22101231978%22">Alzheimer's & dementia : the journal of the Alzheimer's Association</searchLink> [Alzheimers Dement] 2023 Sep; Vol. 19 (9), pp. 4008-4019. <i>Date of Electronic Publication: </i>2023 May 12.
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