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Spatial metabolomics reveals glycogen as an actionable target for pulmonary fibrosis.

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Title: Spatial metabolomics reveals glycogen as an actionable target for pulmonary fibrosis.
Authors: Conroy LR; Department of Neuroscience, University of Kentucky College of Medicine, Lexington, KY, 40536, USA.; Markey Cancer Center, Lexington, KY, 40536, USA., Clarke HA; Department of Biochemistry & Molecular Biology, College of Medicine, University of Florida, Gainesville, FL, 32610, USA., Allison DB; Markey Cancer Center, Lexington, KY, 40536, USA.; Department of Pathology and Laboratory Medicine, University of Kentucky College of Medicine, Lexington, KY, 40536, USA., Valenca SS; Department of Physiology, University of Kentucky College of Medicine, Lexington, KY, 40536, USA.; Saha Cardiovascular Research Center, University of Kentucky, Lexington, KY, 40536, USA., Sun Q; Department of Neuroscience, University of Kentucky College of Medicine, Lexington, KY, 40536, USA., Hawkinson TR; Department of Biochemistry & Molecular Biology, College of Medicine, University of Florida, Gainesville, FL, 32610, USA., Young LEA; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, 40536, USA., Ferreira JE; Department of Pathology and Laboratory Medicine, University of Kentucky College of Medicine, Lexington, KY, 40536, USA., Hammonds AV; Department of Pathology and Laboratory Medicine, University of Kentucky College of Medicine, Lexington, KY, 40536, USA., Dunne JB; Department of Cell & Molecular Pharmacology & Experimental Therapeutics at the Medical University of South Carolina, Charleston, SC, 29425, USA., McDonald RJ; Department of Pathology and Laboratory Medicine, University of Kentucky College of Medicine, Lexington, KY, 40536, USA., Absher KJ; Department of Pathology and Laboratory Medicine, University of Kentucky College of Medicine, Lexington, KY, 40536, USA., Dong BE; Department of Physiology, University of Kentucky College of Medicine, Lexington, KY, 40536, USA.; Saha Cardiovascular Research Center, University of Kentucky, Lexington, KY, 40536, USA., Bruntz RC; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, 40536, USA., Markussen KH; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, 40536, USA., Juras JA; Department of Neuroscience, University of Kentucky College of Medicine, Lexington, KY, 40536, USA.; Markey Cancer Center, Lexington, KY, 40536, USA., Alilain WJ; Department of Neuroscience, University of Kentucky College of Medicine, Lexington, KY, 40536, USA.; Spinal Cord and Brain Injury Research Center, Lexington, KY, 40536, USA., Liu J; Department of Biostatistics, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, 23284, USA., Gentry MS; Markey Cancer Center, Lexington, KY, 40536, USA.; Department of Biochemistry & Molecular Biology, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, 40536, USA.; Center for Advanced Spatial Biomolecule Research, University of Florida, Gainesville, FL, 32610, USA., Angel PM; Department of Cell & Molecular Pharmacology & Experimental Therapeutics at the Medical University of South Carolina, Charleston, SC, 29425, USA., Waters CM; Department of Physiology, University of Kentucky College of Medicine, Lexington, KY, 40536, USA. chris.waters41@uky.edu.; Saha Cardiovascular Research Center, University of Kentucky, Lexington, KY, 40536, USA. chris.waters41@uky.edu., Sun RC; Department of Neuroscience, University of Kentucky College of Medicine, Lexington, KY, 40536, USA. ramonsun@ufl.edu.; Markey Cancer Center, Lexington, KY, 40536, USA. ramonsun@ufl.edu.; Department of Biochemistry & Molecular Biology, College of Medicine, University of Florida, Gainesville, FL, 32610, USA. ramonsun@ufl.edu.; Center for Advanced Spatial Biomolecule Research, University of Florida, Gainesville, FL, 32610, USA. ramonsun@ufl.edu.
Source: Nature communications [Nat Commun] 2023 May 13; Vol. 14 (1), pp. 2759. Date of Electronic Publication: 2023 May 13.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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Department of Neuroscience, University of Kentucky College of Medicine, Lexington, KY, 40536, USA.; Markey Cancer Center, Lexington, KY, 40536, USA.<br /><searchLink fieldCode="AU" term="%22Alilain+WJ%22">Alilain WJ</searchLink>; Department of Neuroscience, University of Kentucky College of Medicine, Lexington, KY, 40536, USA.; Spinal Cord and Brain Injury Research Center, Lexington, KY, 40536, USA.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Department of Biostatistics, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, 23284, USA.<br /><searchLink fieldCode="AU" term="%22Gentry+MS%22">Gentry MS</searchLink>; Markey Cancer Center, Lexington, KY, 40536, USA.; Department of Biochemistry & Molecular Biology, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, 40536, USA.; Center for Advanced Spatial Biomolecule Research, University of Florida, Gainesville, FL, 32610, USA.<br /><searchLink fieldCode="AU" term="%22Angel+PM%22">Angel PM</searchLink>; 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