PD-L1 checkpoint blockade promotes regulatory T cell activity that underlies therapy resistance.
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| Title: | PD-L1 checkpoint blockade promotes regulatory T cell activity that underlies therapy resistance. |
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| Authors: | van Gulijk M; Department of Pulmonary Medicine, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands.; Erasmus MC Cancer Institute, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands., van Krimpen A; Department of Pulmonary Medicine, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands.; Erasmus MC Cancer Institute, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands., Schetters S; Laboratory of Immunoregulation and Mucosal Immunology, VIB-UGent Center for Inflammation Research, Ghent, Belgium., Eterman M; Department of Pulmonary Medicine, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands.; Erasmus MC Cancer Institute, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands., van Elsas M; Department of Medical Oncology, Oncode Institute, Leiden University Medical Center, Leiden, Netherlands., Mankor J; Department of Pulmonary Medicine, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands.; Erasmus MC Cancer Institute, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands., Klaase L; Department of Pulmonary Medicine, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands., de Bruijn M; Department of Pulmonary Medicine, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands., van Nimwegen M; Department of Pulmonary Medicine, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands., van Tienhoven T; Department of Pulmonary Medicine, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands., van Ijcken W; Department of Biomics, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands., Boon L; JJP Biologics, Warsaw, Poland., van der Schoot J; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands., Verdoes M; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.; Institute for Chemical Immunology, Nijmegen, Netherlands., Scheeren F; Department of Dermatology, Leiden University Medical Center, Leiden, Netherlands., van der Burg SH; Department of Medical Oncology, Oncode Institute, Leiden University Medical Center, Leiden, Netherlands., Lambrecht BN; Department of Pulmonary Medicine, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands.; Laboratory of Immunoregulation and Mucosal Immunology, VIB-UGent Center for Inflammation Research, Ghent, Belgium.; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium., Stadhouders R; Department of Pulmonary Medicine, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands.; Department of Cell Biology, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands., Dammeijer F; Department of Pulmonary Medicine, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands.; Erasmus MC Cancer Institute, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands., Aerts J; Department of Pulmonary Medicine, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands.; Erasmus MC Cancer Institute, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands., van Hall T; Department of Medical Oncology, Oncode Institute, Leiden University Medical Center, Leiden, Netherlands. |
| Source: | Science immunology [Sci Immunol] 2023 May 19; Vol. 8 (83), pp. eabn6173. Date of Electronic Publication: 2023 May 19. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2470-9468 |
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| DOI: | 10.1126/sciimmunol.abn6173 |
