Characterisation of IL-23 receptor antagonists and disease relevant mutants using fluorescent probes.

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Title: Characterisation of IL-23 receptor antagonists and disease relevant mutants using fluorescent probes.
Authors: Lay CS; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, NG7 2UH, UK.; Centre of Membrane Proteins and Receptors, University of Birmingham and Nottingham, The Midlands, UK.; Chemical Biology, Medicine Design, GlaxoSmithKline, Stevenage, SG1 2NY, UK., Isidro-Llobet A; Chemical Biology, Medicine Design, GlaxoSmithKline, Stevenage, SG1 2NY, UK., Kilpatrick LE; Centre of Membrane Proteins and Receptors, University of Birmingham and Nottingham, The Midlands, UK.; Division of Bimolecular Science and Medicinal Chemistry, School of Pharmacy, Biodiscovery Institute, University of Nottingham, Nottingham, NG7 2RD, UK., Craggs PD; Chemical Biology, Medicine Design, GlaxoSmithKline, Stevenage, SG1 2NY, UK. peter.d.craggs@gsk.com.; Crick-GSK Biomedical Linklabs, Medicine Design, GlaxoSmithKline, Stevenage, SG1 2NY, UK. peter.d.craggs@gsk.com., Hill SJ; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, NG7 2UH, UK. stephen.hill@nottingham.ac.uk.; Centre of Membrane Proteins and Receptors, University of Birmingham and Nottingham, The Midlands, UK. stephen.hill@nottingham.ac.uk.
Source: Nature communications [Nat Commun] 2023 May 19; Vol. 14 (1), pp. 2882. Date of Electronic Publication: 2023 May 19.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-023-38541-2