Synthesis, biological evaluation, and computational investigation of ethyl 2,4,6-trisubstituted-1,4-dihydropyrimidine-5-carboxylates as potential larvicidal agents against Anopheles arabiensis.

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Title: Synthesis, biological evaluation, and computational investigation of ethyl 2,4,6-trisubstituted-1,4-dihydropyrimidine-5-carboxylates as potential larvicidal agents against Anopheles arabiensis.
Authors: Duraisamy R; Organic Synthesis and Nano-Bio Laboratory, Department of Chemistry, Thiruvalluvar University, Vellore, India., Al-Shar'i NA; Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan., Chandrashekharappa S; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER-R) Raebareli, Lucknow, UP, India., Deb PK; Department of Pharmaceutical Sciences, Faculty of Pharmacy, Philadelphia University, Amman, Jordan., Gleiser RM; CREAN-IMBIV (CONICET-UNC), Universidad Nacional de Cordoba, Cordoba, Argentina., Tratrat C; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Saudi Arabia., Chopra D; Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal, Madhya Pradesh, India., Muthukurpalya Bhojegowd MR; Department of Chemistry, School of Applied Sciences, REVA University, Bangalore, India., Thirumalai D; Organic Synthesis and Nano-Bio Laboratory, Department of Chemistry, Thiruvalluvar University, Vellore, India., Morsy MA; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Saudi Arabia.; Department of Pharmacology, Faculty of Medicine, Minia University, El-Minia, Egypt., Ibrahim YF; Department of Pharmacology, Faculty of Medicine, Minia University, El-Minia, Egypt.; Department of Pathological Sciences, Fakeeh College for Medical Sciences, Jeddah, Saudi Arabia., Mohanlall V; Department of Biotechnology and Food Science, Faculty of Applied Sciences, Durban University of Technology, Durban, South Africa., Venugopala KN; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Saudi Arabia.; Department of Biotechnology and Food Science, Faculty of Applied Sciences, Durban University of Technology, Durban, South Africa.
Source: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2024 May; Vol. 42 (8), pp. 4016-4028. Date of Electronic Publication: 2023 Jun 01.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1538-0254
DOI:10.1080/07391102.2023.2217929