Mechanistic investigation of liver injury induced by BMS-932481, an experimental ɣ-secretase modulator.
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| Title: | Mechanistic investigation of liver injury induced by BMS-932481, an experimental ɣ-secretase modulator. |
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| Authors: | Zhuo X; Pharmaceutical Candidate Optimization, Bristol Myers Squibb, Wallingford, Connecticut, USA., Howell BA; Simulations Plus, Inc., Research Triangle Park, North Carolina, USA., Shen H; Pharmaceutical Candidate Optimization, Bristol Myers Squibb, Lawrenceville, New Jersey, USA., Woodhead JL; Simulations Plus, Inc., Research Triangle Park, North Carolina, USA., Mosure K; Pharmaceutical Candidate Optimization, Bristol Myers Squibb, Wallingford, Connecticut, USA., Zhang Y; Pharmaceutical Candidate Optimization, Bristol Myers Squibb, Lawrenceville, New Jersey, USA., Scialis RJ; Nonclinical Disposition and Pharmacokinetics, Bristol Myers Squibb, Lawrenceville, New Jersey, USA., Iyer R; Nonclinical Disposition and Pharmacokinetics, Bristol Myers Squibb, Lawrenceville, New Jersey, USA., Sun Y; Automation and Assay Technologies, Bristol Myers Squibb, Lawrenceville, New Jersey, USA., Boy KM; Small Molecule Drug Discovery, Bristol Myers Squibb, Wallingford, Connecticut, USA., Lentz KA; Pharmaceutical Candidate Optimization, Bristol Myers Squibb, Wallingford, Connecticut, USA., Denton RR; Pharmaceutical Candidate Optimization, Bristol Myers Squibb, Wallingford, Connecticut, USA., Soars MG; Pharmaceutical Candidate Optimization, Bristol Myers Squibb, Wallingford, Connecticut, USA., Johnson BM; Pharmaceutical Candidate Optimization, Bristol Myers Squibb, Wallingford, Connecticut, USA., Humphreys WG; Pharmaceutical Candidate Optimization, Bristol Myers Squibb, Lawrenceville, New Jersey, USA. |
| Source: | Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2023 Jul 28; Vol. 194 (2), pp. 235-245. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1096-0929 |
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| DOI: | 10.1093/toxsci/kfad057 |
