Metabolomic and transcriptomic analyses of Fmo5-/- mice reveal roles for flavin-containing monooxygenase 5 (FMO5) in NRF2-mediated oxidative stress response, unfolded protein response, lipid homeostasis, and carbohydrate and one-carbon metabolism.
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| Title: | Metabolomic and transcriptomic analyses of Fmo5-/- mice reveal roles for flavin-containing monooxygenase 5 (FMO5) in NRF2-mediated oxidative stress response, unfolded protein response, lipid homeostasis, and carbohydrate and one-carbon metabolism. |
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| Authors: | Phillips IR; Department of Structural and Molecular Biology, University College London, London, United Kingdom.; School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom., Veeravalli S; Department of Structural and Molecular Biology, University College London, London, United Kingdom., Khadayate S; MRC London Institute of Medical Sciences (LMS), London, United Kingdom., Shephard EA; Department of Structural and Molecular Biology, University College London, London, United Kingdom. |
| Source: | PloS one [PLoS One] 2023 Jun 02; Vol. 18 (6), pp. e0286692. Date of Electronic Publication: 2023 Jun 02 (Print Publication: 2023). |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1932-6203 |
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| DOI: | 10.1371/journal.pone.0286692 |
