Rescue of hearing by adenine base editing in a humanized mouse model of Usher syndrome type 1F.

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Bibliographic Details
Title: Rescue of hearing by adenine base editing in a humanized mouse model of Usher syndrome type 1F.
Authors: Peters CW; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Hanlon KS; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA; Department of Neurology, Harvard Medical School and Massachusetts General Hospital, Boston, MA 02114, USA., Ivanchenko MV; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Zinn E; Grousbeck Gene Therapy Center, Schepens Eye Research Institute, Massachusetts Eye and Ear, Boston, MA 02114, USA., Linarte EF; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Li Y; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Levy JM; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA; Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA., Liu DR; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA; Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA., Kleinstiver BP; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Pathology, Harvard Medical School, Boston, MA 02115, USA., Indzhykulian AA; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA; Department of Otolaryngology - Head and Neck Surgery, Harvard Medical School and Massachusetts Eye and Ear, Boston, MA 02114, USA., Corey DP; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: dcorey@hms.harvard.edu.
Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2023 Aug 02; Vol. 31 (8), pp. 2439-2453. Date of Electronic Publication: 2023 Jun 12.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1525-0024
DOI:10.1016/j.ymthe.2023.06.007