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Soluble CD4 effectively prevents excessive TLR activation of resident macrophages in the onset of sepsis.

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Title: Soluble CD4 effectively prevents excessive TLR activation of resident macrophages in the onset of sepsis.
Authors: Zhang SY; CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 210031, China.; The Third People's Hospital of Shenzhen, Shenzhen, 518112, China.; University of Chinese Academy of Sciences, Beijing, 100101, China., Xu QP; CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 210031, China., Shi LN; CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 210031, China.; University of Chinese Academy of Sciences, Beijing, 100101, China., Li SW; CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 210031, China., Wang WH; CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 210031, China., Wang QQ; CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 210031, China., Lu LX; The Laboratory of Genetic Regulators in The Immune System, Xin-xiang Medical University, Xin-xiang, Henan Province, 453003, China., Xiao H; CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 210031, China., Wang JH; CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 210031, China., Li FY; CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 210031, China., Liang YM; The Laboratory of Genetic Regulators in The Immune System, Xin-xiang Medical University, Xin-xiang, Henan Province, 453003, China., Gong ST; The Joint Center of Translational Medicine, Guangzhou Women and Children's Medical Center and Institut Pasteur of Shanghai, Guangzhou, 510623, China., Peng HR; Department of Microbiology, Naval Medical University, Shanghai, 200433, China. phran@126.com., Zhang Z; The Third People's Hospital of Shenzhen, Shenzhen, 518112, China. zhangzheng1975@aliyun.com., Tang H; CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 210031, China. h_tang@zju.edu.cn.; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Centre for Infectious Diseases, Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China. h_tang@zju.edu.cn.
Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2023 Jun 19; Vol. 8 (1), pp. 236. Date of Electronic Publication: 2023 Jun 19.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Soluble CD4 effectively prevents excessive TLR activation of resident macrophages in the onset of sepsis.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+SY%22">Zhang SY</searchLink>; CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 210031, China.; The Third People's Hospital of Shenzhen, Shenzhen, 518112, China.; University of Chinese Academy of Sciences, Beijing, 100101, China.<br /><searchLink fieldCode="AU" term="%22Xu+QP%22">Xu QP</searchLink>; CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 210031, China.<br /><searchLink fieldCode="AU" term="%22Shi+LN%22">Shi LN</searchLink>; CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 210031, China.; University of Chinese Academy of Sciences, Beijing, 100101, China.<br /><searchLink fieldCode="AU" term="%22Li+SW%22">Li SW</searchLink>; CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 210031, China.<br /><searchLink fieldCode="AU" term="%22Wang+WH%22">Wang WH</searchLink>; CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 210031, China.<br /><searchLink fieldCode="AU" term="%22Wang+QQ%22">Wang QQ</searchLink>; CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 210031, China.<br /><searchLink fieldCode="AU" term="%22Lu+LX%22">Lu LX</searchLink>; The Laboratory of Genetic Regulators in The Immune System, Xin-xiang Medical University, Xin-xiang, Henan Province, 453003, China.<br /><searchLink fieldCode="AU" term="%22Xiao+H%22">Xiao H</searchLink>; CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 210031, China.<br /><searchLink fieldCode="AU" term="%22Wang+JH%22">Wang JH</searchLink>; CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 210031, China.<br /><searchLink fieldCode="AU" term="%22Li+FY%22">Li FY</searchLink>; CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 210031, China.<br /><searchLink fieldCode="AU" term="%22Liang+YM%22">Liang YM</searchLink>; The Laboratory of Genetic Regulators in The Immune System, Xin-xiang Medical University, Xin-xiang, Henan Province, 453003, China.<br /><searchLink fieldCode="AU" term="%22Gong+ST%22">Gong ST</searchLink>; The Joint Center of Translational Medicine, Guangzhou Women and Children's Medical Center and Institut Pasteur of Shanghai, Guangzhou, 510623, China.<br /><searchLink fieldCode="AU" term="%22Peng+HR%22">Peng HR</searchLink>; Department of Microbiology, Naval Medical University, Shanghai, 200433, China. phran@126.com.<br /><searchLink fieldCode="AU" term="%22Zhang+Z%22">Zhang Z</searchLink>; The Third People's Hospital of Shenzhen, Shenzhen, 518112, China. zhangzheng1975@aliyun.com.<br /><searchLink fieldCode="AU" term="%22Tang+H%22">Tang H</searchLink>; CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 210031, China. h_tang@zju.edu.cn.; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Centre for Infectious Diseases, Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China. h_tang@zju.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101676423%22">Signal transduction and targeted therapy</searchLink> [Signal Transduct Target Ther] 2023 Jun 19; Vol. 8 (1), pp. 236. <i>Date of Electronic Publication: </i>2023 Jun 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101676423 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2059-3635 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220593635%22">20593635 </searchLink><i>NLM ISO Abbreviation: </i>Signal Transduct Target Ther <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41392-023-01438-z
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              Text: 2023 Jun 19
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