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Novel Strategy to Combat the Procoagulant Phenotype in Heparin-Induced Thrombocytopenia Using 12-LOX Inhibition.

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Title: Novel Strategy to Combat the Procoagulant Phenotype in Heparin-Induced Thrombocytopenia Using 12-LOX Inhibition.
Authors: Renna SA; The Cardeza Foundation for Hematologic Research, Center for Hemostasis, Thrombosis and Vascular Biology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA (S.A.R., X.Z., P.M., J.V.M., S.E.M.)., Zhao X; The Cardeza Foundation for Hematologic Research, Center for Hemostasis, Thrombosis and Vascular Biology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA (S.A.R., X.Z., P.M., J.V.M., S.E.M.)., Kunapuli SP; Sol Sherry Thrombosis Center and the Department of Physiology, Temple University School of Medicine, Philadelphia, PA (S.P.K.)., Ma P; The Cardeza Foundation for Hematologic Research, Center for Hemostasis, Thrombosis and Vascular Biology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA (S.A.R., X.Z., P.M., J.V.M., S.E.M.)., Holinstat M; Department of Pharmacology, University of Michigan, Ann Arbor (M.H.)., Boxer MB; Veralox Therapeutics, Frederick, MD (M.B.B., D.J.M.)., Maloney DJ; Veralox Therapeutics, Frederick, MD (M.B.B., D.J.M.)., Michael JV; The Cardeza Foundation for Hematologic Research, Center for Hemostasis, Thrombosis and Vascular Biology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA (S.A.R., X.Z., P.M., J.V.M., S.E.M.)., McKenzie SE; The Cardeza Foundation for Hematologic Research, Center for Hemostasis, Thrombosis and Vascular Biology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA (S.A.R., X.Z., P.M., J.V.M., S.E.M.).
Source: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2023 Oct; Vol. 43 (10), pp. 1808-1817. Date of Electronic Publication: 2023 Jun 22.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505803 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4636 (Electronic) Linking ISSN: 10795642 NLM ISO Abbreviation: Arterioscler Thromb Vasc Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Novel Strategy to Combat the Procoagulant Phenotype in Heparin-Induced Thrombocytopenia Using 12-LOX Inhibition.
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  Data: <searchLink fieldCode="AU" term="%22Renna+SA%22">Renna SA</searchLink>; The Cardeza Foundation for Hematologic Research, Center for Hemostasis, Thrombosis and Vascular Biology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA (S.A.R., X.Z., P.M., J.V.M., S.E.M.).<br /><searchLink fieldCode="AU" term="%22Zhao+X%22">Zhao X</searchLink>; The Cardeza Foundation for Hematologic Research, Center for Hemostasis, Thrombosis and Vascular Biology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA (S.A.R., X.Z., P.M., J.V.M., S.E.M.).<br /><searchLink fieldCode="AU" term="%22Kunapuli+SP%22">Kunapuli SP</searchLink>; Sol Sherry Thrombosis Center and the Department of Physiology, Temple University School of Medicine, Philadelphia, PA (S.P.K.).<br /><searchLink fieldCode="AU" term="%22Ma+P%22">Ma P</searchLink>; The Cardeza Foundation for Hematologic Research, Center for Hemostasis, Thrombosis and Vascular Biology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA (S.A.R., X.Z., P.M., J.V.M., S.E.M.).<br /><searchLink fieldCode="AU" term="%22Holinstat+M%22">Holinstat M</searchLink>; Department of Pharmacology, University of Michigan, Ann Arbor (M.H.).<br /><searchLink fieldCode="AU" term="%22Boxer+MB%22">Boxer MB</searchLink>; Veralox Therapeutics, Frederick, MD (M.B.B., D.J.M.).<br /><searchLink fieldCode="AU" term="%22Maloney+DJ%22">Maloney DJ</searchLink>; Veralox Therapeutics, Frederick, MD (M.B.B., D.J.M.).<br /><searchLink fieldCode="AU" term="%22Michael+JV%22">Michael JV</searchLink>; The Cardeza Foundation for Hematologic Research, Center for Hemostasis, Thrombosis and Vascular Biology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA (S.A.R., X.Z., P.M., J.V.M., S.E.M.).<br /><searchLink fieldCode="AU" term="%22McKenzie+SE%22">McKenzie SE</searchLink>; The Cardeza Foundation for Hematologic Research, Center for Hemostasis, Thrombosis and Vascular Biology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA (S.A.R., X.Z., P.M., J.V.M., S.E.M.).
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  Data: <searchLink fieldCode="JN" term="%229505803%22">Arteriosclerosis, thrombosis, and vascular biology</searchLink> [Arterioscler Thromb Vasc Biol] 2023 Oct; Vol. 43 (10), pp. 1808-1817. <i>Date of Electronic Publication: </i>2023 Jun 22.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott+Williams+%26+Wilkins%22">Lippincott Williams & Wilkins </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9505803 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1524-4636 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210795642%22">10795642 </searchLink><i>NLM ISO Abbreviation: </i>Arterioscler Thromb Vasc Biol <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1161/ATVBAHA.123.319434
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      – Code: eng
        Text: English
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        StartPage: 1808
    Titles:
      – TitleFull: Novel Strategy to Combat the Procoagulant Phenotype in Heparin-Induced Thrombocytopenia Using 12-LOX Inhibition.
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          Name:
            NameFull: Renna SA
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            NameFull: Zhao X
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            NameFull: Kunapuli SP
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            NameFull: Ma P
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            NameFull: Holinstat M
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            NameFull: Boxer MB
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            NameFull: Maloney DJ
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            NameFull: Michael JV
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            NameFull: McKenzie SE
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            – D: 01
              M: 10
              Text: 2023 Oct
              Type: published
              Y: 2023
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              Value: 43
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            – TitleFull: Arteriosclerosis, thrombosis, and vascular biology
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