Evaluating the efficacy and safety of neoadjuvant pembrolizumab in patients with stage I-III MMR-deficient colon cancer: a national, multicentre, prospective, single-arm, phase II study protocol.

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Title: Evaluating the efficacy and safety of neoadjuvant pembrolizumab in patients with stage I-III MMR-deficient colon cancer: a national, multicentre, prospective, single-arm, phase II study protocol.
Authors: Justesen TF; Center for Surgical Science, Zealand University Hospital, Koge, Denmark toju@regionsjaelland.dk., Gögenur I; Center for Surgical Science, Zealand University Hospital, Koge, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Tarpgaard LS; Department of Oncology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Pfeiffer P; Department of Oncology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Qvortrup C; Department of Oncology, Rigshospitalet, Copenhagen, Denmark.
Source: BMJ open [BMJ Open] 2023 Jun 22; Vol. 13 (6), pp. e073372. Date of Electronic Publication: 2023 Jun 22.
Publication Type: Clinical Trial Protocol; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2044-6055
DOI:10.1136/bmjopen-2023-073372