Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation.
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| Title: | Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation. |
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| Authors: | Rodina A; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Xu C; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Digwal CS; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Joshi S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Patel Y; Department of Biochemistry, Groupe de Recherche Axé sur la Structure des Protéines, McGill University, Montreal, QC, H3G 0B1, Canada., Santhaseela AR; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Bay S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Merugu S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Alam A; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Yan P; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Yang C; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.; Changhai Hospital, Second Military Medical University, Shanghai, China., Roychowdhury T; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Panchal P; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Shrestha L; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Kang Y; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Sharma S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Almodovar J; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Corben A; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.; Maimonides Medical Center, Brooklyn, NY, USA., Alpaugh ML; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.; Rowan University, Glassboro, NJ, USA., Modi S; Department of Medicine, Division of Solid Tumors, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Guzman ML; Department of Medicine, Division of Hematology Oncology, Weill Cornell Medicine, New York, NY, 10065, USA., Fei T; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Taldone T; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Ginsberg SD; Departments of Psychiatry, Neuroscience & Physiology & the NYU Neuroscience Institute, NYU Grossman School of Medicine, New York, NY, 10016, USA.; Center for Dementia Research, Nathan Kline Institute, Orangeburg, NY, 10962, USA., Erdjument-Bromage H; Department of Neuroscience and Physiology and Neuroscience Institute, NYU Grossman School of Medicine, New York, NY, 10016, USA., Neubert TA; Department of Neuroscience and Physiology and Neuroscience Institute, NYU Grossman School of Medicine, New York, NY, 10016, USA., Manova-Todorova K; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Tsou MB; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Young JC; Department of Biochemistry, Groupe de Recherche Axé sur la Structure des Protéines, McGill University, Montreal, QC, H3G 0B1, Canada., Wang T; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA. wangtaifr@gmail.com., Chiosis G; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA. chiosisg@mskcc.org.; Department of Medicine, Division of Solid Tumors, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA. chiosisg@mskcc.org. |
| Source: | Nature communications [Nat Commun] 2023 Jun 23; Vol. 14 (1), pp. 3742. Date of Electronic Publication: 2023 Jun 23. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-023-39241-7 |
