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Genome analysis of Cephalotrichum gorgonifer and identification of the biosynthetic pathway for rasfonin, an inhibitor of KRAS dependent cancer.

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Title: Genome analysis of Cephalotrichum gorgonifer and identification of the biosynthetic pathway for rasfonin, an inhibitor of KRAS dependent cancer.
Authors: Schüller A; Department of Applied Genetics and Cell Biology, Institute of Microbial Genetics, University of Natural Resources and Life Sciences, Vienna (BOKU), Campus Tulln, Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria., Studt-Reinhold L; Department of Applied Genetics and Cell Biology, Institute of Microbial Genetics, University of Natural Resources and Life Sciences, Vienna (BOKU), Campus Tulln, Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria., Berger H; Department of Applied Genetics and Cell Biology, Institute of Microbial Genetics, University of Natural Resources and Life Sciences, Vienna (BOKU), Campus Tulln, Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria., Silvestrini L; Department of Applied Genetics and Cell Biology, Institute of Microbial Genetics, University of Natural Resources and Life Sciences, Vienna (BOKU), Campus Tulln, Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria.; DGforLife, Operations - Research and Development, Via Albert Einstein, Marcallo c.C., 20010, Milan, Italy., Labuda R; Research Platform Bioactive Microbial Metabolites (BiMM), Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria.; Department for Farm Animals and Veterinary Public Health, Institute of Food Safety, Food Technology and Veterinary Public Health, Unit of Food Microbiology, University of Veterinary Medicine Vienna, Veterinaerplatz 1, 1210, Vienna, Austria., Güldener U; Department of Bioinformatics, Technical University of Munich, TUM School of Life Sciences Weihenstephan, Freising, Germany.; German Heart Center Munich, Technical University Munich, Lazarettstraße 36, 80636, Munich, Germany., Gorfer M; AIT Austrian Institute of Technology GmbH, Bioresources, 3430, Tulln, Austria., Bacher M; Research Platform Bioactive Microbial Metabolites (BiMM), Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria.; Department of Chemistry, Institute of Chemistry of Renewable Resources, University of Natural Resources and Life Sciences Vienna (BOKU), Konrad-LorenzStraße 24, 3430, Tulln, Austria., Doppler M; Department of Agrobiotechnology (IFA-Tulln), Institute of Bioanalytics and Agro-Metabolomics, University of Natural Resources and Life Sciences, Vienna (BOKU), Konrad Lorenz Strasse 20, 3430, Tulln an der Donau, Austria.; Core Facility Bioactive Molecules, Screening and Analysis, University of Natural Resources and Life Sciences, Vienna, 3430, Tulln an der Donau, Austria., Gasparotto E; Department of Applied Genetics and Cell Biology, Institute of Microbial Genetics, University of Natural Resources and Life Sciences, Vienna (BOKU), Campus Tulln, Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria.; Research Platform Bioactive Microbial Metabolites (BiMM), Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria.; Department of Biological Chemistry, Faculty of Chemistry, University of Vienna, Josef-Holaubek-Platz 2, 1090, Vienna, Austria., Gattesco A; Department of Applied Genetics and Cell Biology, Institute of Microbial Genetics, University of Natural Resources and Life Sciences, Vienna (BOKU), Campus Tulln, Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria.; Research Platform Bioactive Microbial Metabolites (BiMM), Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria., Sulyok M; Department of Agrobiotechnology (IFA-Tulln), Institute of Bioanalytics and Agro-Metabolomics, University of Natural Resources and Life Sciences, Vienna (BOKU), Konrad Lorenz Strasse 20, 3430, Tulln an der Donau, Austria., Strauss J; Department of Applied Genetics and Cell Biology, Institute of Microbial Genetics, University of Natural Resources and Life Sciences, Vienna (BOKU), Campus Tulln, Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria. joseph.strauss@boku.ac.at.; Research Platform Bioactive Microbial Metabolites (BiMM), Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria. joseph.strauss@boku.ac.at.
Source: Fungal biology and biotechnology [Fungal Biol Biotechnol] 2023 Jun 24; Vol. 10 (1), pp. 13. Date of Electronic Publication: 2023 Jun 24.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101655873 Publication Model: Electronic Cited Medium: Internet ISSN: 2054-3085 (Electronic) Linking ISSN: 20543085 NLM ISO Abbreviation: Fungal Biol Biotechnol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Genome analysis of Cephalotrichum gorgonifer and identification of the biosynthetic pathway for rasfonin, an inhibitor of KRAS dependent cancer.
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  Data: <searchLink fieldCode="AU" term="%22Schüller+A%22">Schüller A</searchLink>; Department of Applied Genetics and Cell Biology, Institute of Microbial Genetics, University of Natural Resources and Life Sciences, Vienna (BOKU), Campus Tulln, Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria.<br /><searchLink fieldCode="AU" term="%22Studt-Reinhold+L%22">Studt-Reinhold L</searchLink>; Department of Applied Genetics and Cell Biology, Institute of Microbial Genetics, University of Natural Resources and Life Sciences, Vienna (BOKU), Campus Tulln, Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria.<br /><searchLink fieldCode="AU" term="%22Berger+H%22">Berger H</searchLink>; Department of Applied Genetics and Cell Biology, Institute of Microbial Genetics, University of Natural Resources and Life Sciences, Vienna (BOKU), Campus Tulln, Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria.<br /><searchLink fieldCode="AU" term="%22Silvestrini+L%22">Silvestrini L</searchLink>; Department of Applied Genetics and Cell Biology, Institute of Microbial Genetics, University of Natural Resources and Life Sciences, Vienna (BOKU), Campus Tulln, Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria.; DGforLife, Operations - Research and Development, Via Albert Einstein, Marcallo c.C., 20010, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Labuda+R%22">Labuda R</searchLink>; Research Platform Bioactive Microbial Metabolites (BiMM), Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria.; Department for Farm Animals and Veterinary Public Health, Institute of Food Safety, Food Technology and Veterinary Public Health, Unit of Food Microbiology, University of Veterinary Medicine Vienna, Veterinaerplatz 1, 1210, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Güldener+U%22">Güldener U</searchLink>; Department of Bioinformatics, Technical University of Munich, TUM School of Life Sciences Weihenstephan, Freising, Germany.; German Heart Center Munich, Technical University Munich, Lazarettstraße 36, 80636, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Gorfer+M%22">Gorfer M</searchLink>; AIT Austrian Institute of Technology GmbH, Bioresources, 3430, Tulln, Austria.<br /><searchLink fieldCode="AU" term="%22Bacher+M%22">Bacher M</searchLink>; Research Platform Bioactive Microbial Metabolites (BiMM), Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria.; Department of Chemistry, Institute of Chemistry of Renewable Resources, University of Natural Resources and Life Sciences Vienna (BOKU), Konrad-LorenzStraße 24, 3430, Tulln, Austria.<br /><searchLink fieldCode="AU" term="%22Doppler+M%22">Doppler M</searchLink>; Department of Agrobiotechnology (IFA-Tulln), Institute of Bioanalytics and Agro-Metabolomics, University of Natural Resources and Life Sciences, Vienna (BOKU), Konrad Lorenz Strasse 20, 3430, Tulln an der Donau, Austria.; Core Facility Bioactive Molecules, Screening and Analysis, University of Natural Resources and Life Sciences, Vienna, 3430, Tulln an der Donau, Austria.<br /><searchLink fieldCode="AU" term="%22Gasparotto+E%22">Gasparotto E</searchLink>; Department of Applied Genetics and Cell Biology, Institute of Microbial Genetics, University of Natural Resources and Life Sciences, Vienna (BOKU), Campus Tulln, Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria.; Research Platform Bioactive Microbial Metabolites (BiMM), Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria.; Department of Biological Chemistry, Faculty of Chemistry, University of Vienna, Josef-Holaubek-Platz 2, 1090, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Gattesco+A%22">Gattesco A</searchLink>; Department of Applied Genetics and Cell Biology, Institute of Microbial Genetics, University of Natural Resources and Life Sciences, Vienna (BOKU), Campus Tulln, Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria.; Research Platform Bioactive Microbial Metabolites (BiMM), Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria.<br /><searchLink fieldCode="AU" term="%22Sulyok+M%22">Sulyok M</searchLink>; Department of Agrobiotechnology (IFA-Tulln), Institute of Bioanalytics and Agro-Metabolomics, University of Natural Resources and Life Sciences, Vienna (BOKU), Konrad Lorenz Strasse 20, 3430, Tulln an der Donau, Austria.<br /><searchLink fieldCode="AU" term="%22Strauss+J%22">Strauss J</searchLink>; Department of Applied Genetics and Cell Biology, Institute of Microbial Genetics, University of Natural Resources and Life Sciences, Vienna (BOKU), Campus Tulln, Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria. joseph.strauss@boku.ac.at.; Research Platform Bioactive Microbial Metabolites (BiMM), Konrad Lorenz Strasse 24, 3430, Tulln an der Donau, Austria. joseph.strauss@boku.ac.at.
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