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Patient-derived xenograft models of ALK+ ALCL reveal preclinical promise for therapy with brigatinib.

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Title: Patient-derived xenograft models of ALK+ ALCL reveal preclinical promise for therapy with brigatinib.
Authors: Prokoph N; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK., Matthews JD; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK., Trigg RM; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK., Montes-Mojarro IA; Institute of Pathology and Neuropathology and Comprehensive Cancer Center Tübingen, University Hospital Tübingen, Eberhard-Karls-University, Tübingen, Germany., Burke GAA; Department of Paediatric Haematology and Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Fend F; Institute of Pathology and Neuropathology and Comprehensive Cancer Center Tübingen, University Hospital Tübingen, Eberhard-Karls-University, Tübingen, Germany., Merkel O; Department of Experimental Pathology and Laboratory Animal Pathology, Institute of Clinical Pathology, Medical University of Vienna, Vienna, Austria., Kenner L; Department of Experimental Pathology and Laboratory Animal Pathology, Institute of Clinical Pathology, Medical University of Vienna, Vienna, Austria.; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, Austria.; Christian Doppler Laboratory for Applied Metabolomics, Medical University of Vienna, Vienna, Austria.; Center for Biomarker Research in Medicine (CBmed) Vienna, Core-Lab2, Medical University of Vienna, Vienna, Austria., Geoerger B; Department of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Center, Villejuif, France.; INSERM U1015, Gustave Roussy Cancer Center, Université Paris-Saclay, Villejuif, France., Johnston R; Department of Paediatric Oncology/Haematology, Royal Belfast Hospital for Sick Children, Belfast, UK., Murray MJ; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.; Department of Paediatric Haematology and Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Riguad C; Department of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Center, Villejuif, France., Brugières L; Department of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Center, Villejuif, France., Turner SD; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.; Institute of Medical Genetics and Genomics, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Source: British journal of haematology [Br J Haematol] 2023 Sep; Vol. 202 (5), pp. 985-994. Date of Electronic Publication: 2023 Jun 25.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2141 (Electronic) Linking ISSN: 00071048 NLM ISO Abbreviation: Br J Haematol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Patient-derived xenograft models of ALK+ ALCL reveal preclinical promise for therapy with brigatinib.
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  Data: <searchLink fieldCode="AU" term="%22Prokoph+N%22">Prokoph N</searchLink>; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Matthews+JD%22">Matthews JD</searchLink>; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Trigg+RM%22">Trigg RM</searchLink>; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Montes-Mojarro+IA%22">Montes-Mojarro IA</searchLink>; Institute of Pathology and Neuropathology and Comprehensive Cancer Center Tübingen, University Hospital Tübingen, Eberhard-Karls-University, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Burke+GAA%22">Burke GAA</searchLink>; Department of Paediatric Haematology and Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Fend+F%22">Fend F</searchLink>; Institute of Pathology and Neuropathology and Comprehensive Cancer Center Tübingen, University Hospital Tübingen, Eberhard-Karls-University, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Merkel+O%22">Merkel O</searchLink>; Department of Experimental Pathology and Laboratory Animal Pathology, Institute of Clinical Pathology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Kenner+L%22">Kenner L</searchLink>; Department of Experimental Pathology and Laboratory Animal Pathology, Institute of Clinical Pathology, Medical University of Vienna, Vienna, Austria.; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, Austria.; Christian Doppler Laboratory for Applied Metabolomics, Medical University of Vienna, Vienna, Austria.; Center for Biomarker Research in Medicine (CBmed) Vienna, Core-Lab2, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Geoerger+B%22">Geoerger B</searchLink>; Department of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Center, Villejuif, France.; INSERM U1015, Gustave Roussy Cancer Center, Université Paris-Saclay, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Johnston+R%22">Johnston R</searchLink>; Department of Paediatric Oncology/Haematology, Royal Belfast Hospital for Sick Children, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Murray+MJ%22">Murray MJ</searchLink>; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.; Department of Paediatric Haematology and Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Riguad+C%22">Riguad C</searchLink>; Department of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Center, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Brugières+L%22">Brugières L</searchLink>; Department of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Center, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Turner+SD%22">Turner SD</searchLink>; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.; Institute of Medical Genetics and Genomics, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
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  Data: <searchLink fieldCode="JN" term="%220372544%22">British journal of haematology</searchLink> [Br J Haematol] 2023 Sep; Vol. 202 (5), pp. 985-994. <i>Date of Electronic Publication: </i>2023 Jun 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0372544 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1365-2141 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200071048%22">00071048 </searchLink><i>NLM ISO Abbreviation: </i>Br J Haematol <i>Subsets: </i>MEDLINE
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