Higher testosterone and testosterone/estradiol ratio in men are associated with decreased Pheno-/GrimAge and DNA-methylation based PAI1.
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| Title: | Higher testosterone and testosterone/estradiol ratio in men are associated with decreased Pheno-/GrimAge and DNA-methylation based PAI1. |
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| Authors: | Kusters CDJ; Department of Human Genetics, David Geffen School of Medicine, Los Angeles, CA, USA. ckusters@ucla.edu.; Department of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA, USA. ckusters@ucla.edu.; Department of Epidemiology, Fielding School of Public Health at UCLA, Box 708822, 650 Charles E. Young Drive South, CA, 90095-7088, Los Angeles, USA. ckusters@ucla.edu., Paul KC; Department of Neurology, David Geffen School of Medicine, Los Angeles, CA, USA., Lu AT; Department of Human Genetics, David Geffen School of Medicine, Los Angeles, CA, USA.; Altos Labs, San Diego, USA., Ferruci L; Longitudinal Studies Section, Translational Gerontology Branch, National Institute On Aging, National Institutes of Health, Baltimore, USA., Ritz BR; Department of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA, USA.; Department of Neurology, David Geffen School of Medicine, Los Angeles, CA, USA.; Department of Environmental Health, UCLA Fielding School of Public Health, Los Angeles, CA, USA., Binder AM; Department of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA, USA.; Population Sciences in the Pacific Program, University of Hawaii Cancer Center, Honolulu, HI, USA., Horvath S; Department of Human Genetics, David Geffen School of Medicine, Los Angeles, CA, USA.; Altos Labs, San Diego, USA.; Department of Biostatistics, School of Public Health, University of California, Los Angeles, Los Angeles, CA, USA. |
| Source: | GeroScience [Geroscience] 2024 Feb; Vol. 46 (1), pp. 1053-1069. Date of Electronic Publication: 2023 Jun 27. |
| Publication Type: | Journal Article; Research Support, N.I.H., Intramural; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2509-2723 |
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| DOI: | 10.1007/s11357-023-00832-3 |
