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Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1.

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Title: Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1.
Authors: Zhang T; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Xu D; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 201203 Shanghai, China.; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA., Trefts E; The Salk Institute for Biological Studies, La Jolla, CA 92037, USA., Lv M; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Inuzuka H; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Song G; Division of Endocrinology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA., Liu M; Transfusion Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA., Lu J; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Liu J; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 201203 Shanghai, China., Chu C; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA., Wang M; Department of Biliary-Pancreatic Surgery, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030 Wuhan, Hubei, China., Wang H; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA., Meng H; F.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA 02115, USA., Liu H; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Zhuang Y; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Xie X; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 201203 Shanghai, China., Dang F; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Guan D; Division of Endocrinology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA., Men Y; Division of Endocrinology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA., Jiang S; Division of Endocrinology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Metabolic and Bariatric Surgery, The First Affiliated Hospital of Jinan University, 510632 Guangzhou, China., Jiang C; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Dai X; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Liu J; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Wang Z; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Yan P; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Wang J; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Tu Z; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Babuta M; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Erickson E; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Hillis AL; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Dibble CC; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Asara JM; Division of Signal Transduction, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Szabo G; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Sicinski P; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.; Department of Histology and Embryology, Center for Biostructure Research, Medical University of Warsaw, 02-004 Warsaw, Poland., Miao J; Division of Endocrinology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA., Lee YR; Institute of Biomedical Sciences, Academia Sinica, Taipei 115201, Taiwan., Pan L; State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 200032 Shanghai, China., Shaw RJ; The Salk Institute for Biological Studies, La Jolla, CA 92037, USA., Yuan J; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 201203 Shanghai, China.; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA., Wei W; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Source: Science (New York, N.Y.) [Science] 2023 Jun 30; Vol. 380 (6652), pp. 1372-1380. Date of Electronic Publication: 2023 Jun 29.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1095-9203
DOI:10.1126/science.abn1725