Dysregulated IFN-γ signals promote autoimmunity in STAT1 gain-of-function syndrome.

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Title: Dysregulated IFN-γ signals promote autoimmunity in STAT1 gain-of-function syndrome.
Authors: Largent AD; Seattle Children's Research Institute, Seattle, WA 98101, USA., Lambert K; Benaroya Research Institute, Seattle, WA 98101, USA., Chiang K; Seattle Children's Research Institute, Seattle, WA 98101, USA., Shumlak N; Seattle Children's Research Institute, Seattle, WA 98101, USA., Liggitt D; Department of Comparative Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA., Oukka M; Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98195, USA.; Department of Immunology, University of Washington School of Medicine, Seattle, WA 98195, USA., Torgerson TR; Allen Institute for Immunology, Seattle, WA 98109, USA., Buckner JH; Benaroya Research Institute, Seattle, WA 98101, USA., Allenspach EJ; Seattle Children's Research Institute, Seattle, WA 98101, USA.; Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98195, USA., Rawlings DJ; Seattle Children's Research Institute, Seattle, WA 98101, USA.; Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98195, USA.; Department of Immunology, University of Washington School of Medicine, Seattle, WA 98195, USA., Jackson SW; Seattle Children's Research Institute, Seattle, WA 98101, USA.; Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98195, USA.; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA 98195, USA.
Source: Science translational medicine [Sci Transl Med] 2023 Jul 05; Vol. 15 (703), pp. eade7028. Date of Electronic Publication: 2023 Jul 05.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1946-6242
DOI:10.1126/scitranslmed.ade7028