Complement is activated by elevated IgG3 hexameric platforms and deposits C4b onto distinct antibody domains.
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| Title: | Complement is activated by elevated IgG3 hexameric platforms and deposits C4b onto distinct antibody domains. |
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| Authors: | Abendstein L; Department of Cell and Chemical Biology, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands., Dijkstra DJ; Department of Immunology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., Tjokrodirijo RTN; Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., van Veelen PA; Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., Trouw LA; Department of Immunology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., Hensbergen PJ; Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., Sharp TH; Department of Cell and Chemical Biology, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands. t.sharp@lumc.nl. |
| Source: | Nature communications [Nat Commun] 2023 Jul 07; Vol. 14 (1), pp. 4027. Date of Electronic Publication: 2023 Jul 07. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-023-39788-5 |
