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Thromboxane biosynthesis in cancer patients and its inhibition by aspirin: a sub-study of the Add-Aspirin trial.

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Title: Thromboxane biosynthesis in cancer patients and its inhibition by aspirin: a sub-study of the Add-Aspirin trial.
Authors: Joharatnam-Hogan N; MRC Clinical Trials Unit, UCL, London, UK., Hatem D; Department of Safety and Bioethics, Division of Pharmacology, Catholic University School of Medicine, Rome, Italy., Cafferty FH; MRC Clinical Trials Unit, UCL, London, UK.; The Institute of Cancer Research, London, UK., Petrucci G; Department of Safety and Bioethics, Division of Pharmacology, Catholic University School of Medicine, Rome, Italy., Cameron DA; Cancer Research UK Edinburgh Centre, Institute of Genetics and Cancer, The University of Edinburgh, Western General Hospital, Edinburgh, UK., Ring A; The Institute of Cancer Research, London, UK.; The Royal Marsden NHS Foundation Trust, London, UK., Kynaston HG; Department of Urology, Cardiff University School of Medicine, Cardiff, UK., Gilbert DC; MRC Clinical Trials Unit, UCL, London, UK.; University Hospitals Sussex NHS Foundation Trust, Brighton, UK., Wilson RH; School of Cancer Sciences, University of Glasgow, Glasgow, UK.; The Beatson West of Scotland Cancer Centre, Glasgow, UK., Hubner RA; The Christie NHS Foundation Trust, Department of Medical Oncology, Manchester, UK.; University of Manchester, Division of Cancer Sciences, Manchester, UK., Swinson DEB; Leeds Teaching Hospitals NHS Trust, Leeds, UK., Cleary S; MRC Clinical Trials Unit, UCL, London, UK., Robbins A; MRC Clinical Trials Unit, UCL, London, UK., MacKenzie M; Independent Cancer Patients' Voice, London, UK., Scott-Brown MWG; University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK., Sothi S; University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK., Dawson LK; Edinburgh Cancer Centre, Western General Hospital, Edinburgh, UK., Capaldi LM; Worcestershire Acute Hospitals NHS Trust, Worcester, UK., Churn M; Worcestershire Acute Hospitals NHS Trust, Worcester, UK., Cunningham D; The Royal Marsden NHS Foundation Trust, London, UK., Khoo V; The Institute of Cancer Research, London, UK.; The Royal Marsden NHS Foundation Trust, London, UK., Armstrong AC; The Christie NHS Foundation Trust, Department of Medical Oncology, Manchester, UK., Ainsworth NL; The Queen Elizabeth Hospital King's Lynn NHS Foundation Trust, King's Lynn, UK., Horan G; The Queen Elizabeth Hospital King's Lynn NHS Foundation Trust, King's Lynn, UK., Wheatley DA; Royal Cornwall Hospitals NHS Trust, Cornwall, UK., Mullen R; The Highland Breast Centre, Raigmore Hospital, Inverness, UK., Lofts FJ; St George's University Hospitals NHS Foundation Trust, London, UK., Walther A; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK., Herbertson RA; University Hospitals Sussex NHS Foundation Trust, Brighton, UK., Eaton JD; University Hospitals of Morecambe Bay NHS Foundation Trust, Kendal, UK., O'Callaghan A; Portsmouth Hospitals University NHS Trust, Portsmouth, UK., Eichholz A; Buckinghamshire Healthcare NHS Trust, Buckinghamshire, UK., Kagzi MM; South Tees Hospitals NHS Foundation Trust, Middlesbrough, UK., Patterson DM; West Suffolk Hospitals NHS Trust, St Edmunds, UK., Narahari K; University Hospital of Wales, Cardiff and Vale University Health Board, Cardiff, UK.; Division of Cancer and Genetics, Cardiff University, Cardiff, UK., Bradbury J; Salisbury NHS Foundation Trust, Salisbury, UK., Stokes Z; United Lincolnshire Hospitals NHS Trust, Lincoln City, UK., Rizvi AJ; Milton Keynes University Hospital NHS Foundation Trust, Milton Keynes, UK., Walker GA; Nottingham University Hospitals NHS Trust, Nottingham, UK., Kunene VL; Walsall Manor Hospital and University Hospitals, Birmingham NHS Foundation Trust, Birmingham, UK., Srihari N; Shrewsbury and Telford Hospital NHS Trust, Shrewsbury, UK., Gentry-Maharaj A; MRC Clinical Trials Unit, UCL, London, UK., Meade A; MRC Clinical Trials Unit, UCL, London, UK., Patrono C; Department of Safety and Bioethics, Division of Pharmacology, Catholic University School of Medicine, Rome, Italy., Rocca B; Department of Safety and Bioethics, Division of Pharmacology, Catholic University School of Medicine, Rome, Italy., Langley RE; MRC Clinical Trials Unit, UCL, London, UK. ruth.langley@ucl.ac.uk.
Source: British journal of cancer [Br J Cancer] 2023 Sep; Vol. 129 (4), pp. 706-720. Date of Electronic Publication: 2023 Jul 07.
Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1827 (Electronic) Linking ISSN: 00070920 NLM ISO Abbreviation: Br J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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