LSD1 promotes prostate cancer reprogramming by repressing TP53 signaling independently of its demethylase function.

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Title: LSD1 promotes prostate cancer reprogramming by repressing TP53 signaling independently of its demethylase function.
Authors: Kumaraswamy A; Department of Internal Medicine and.; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA., Duan Z; Department of Internal Medicine and.; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA., Flores D; Department of Internal Medicine and.; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA., Zhang C; Department of Internal Medicine and.; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA., Sehrawat A; Knight Cancer Institute and., Hu YM; Knight Cancer Institute and.; Biomedical Engineering Department, Oregon Health & Science University (OHSU), Portland, Oregon, USA., Swaim OA; Department of Internal Medicine and.; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.; College of Literature, Science, and the Arts, and., Rodansky E; Department of Internal Medicine and.; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA., Storck WK; Department of Internal Medicine and.; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA., Kuleape JA; Department of Internal Medicine and.; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA., Bedi K; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.; Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA., Mannan R; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Wang XM; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Michigan Center for Translational Pathology, Ann Arbor, Michigan, USA., Udager A; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Ravikumar V; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA., Bankhead A 3rd; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA., Coleman I; Divisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Lee JK; Divisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Morrissey C; Department of Urology, University of Washington, Seattle, Washington, USA., Nelson PS; Divisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Chinnaiyan AM; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Michigan Center for Translational Pathology, Ann Arbor, Michigan, USA.; Department of Urology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Howard Hughes Medical Institute, Ann Arbor, Michigan, USA., Rao A; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.; Department of Radiation Oncology and.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA., Xia Z; Knight Cancer Institute and.; Biomedical Engineering Department, Oregon Health & Science University (OHSU), Portland, Oregon, USA., Yates JA; Department of Internal Medicine and.; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA., Alumkal JJ; Department of Internal Medicine and.; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.; Michigan Center for Translational Pathology, Ann Arbor, Michigan, USA.
Source: JCI insight [JCI Insight] 2023 Aug 08; Vol. 8 (15). Date of Electronic Publication: 2023 Aug 08.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
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  Data: LSD1 promotes prostate cancer reprogramming by repressing TP53 signaling independently of its demethylase function.
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  Data: <searchLink fieldCode="AU" term="%22Kumaraswamy+A%22">Kumaraswamy A</searchLink>; Department of Internal Medicine and.; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Duan+Z%22">Duan Z</searchLink>; Department of Internal Medicine and.; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Flores+D%22">Flores D</searchLink>; Department of Internal Medicine and.; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Department of Internal Medicine and.; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Sehrawat+A%22">Sehrawat A</searchLink>; Knight Cancer Institute and.<br /><searchLink fieldCode="AU" term="%22Hu+YM%22">Hu YM</searchLink>; Knight Cancer Institute and.; Biomedical Engineering Department, Oregon Health & Science University (OHSU), Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Swaim+OA%22">Swaim OA</searchLink>; Department of Internal Medicine and.; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.; College of Literature, Science, and the Arts, and.<br /><searchLink fieldCode="AU" term="%22Rodansky+E%22">Rodansky E</searchLink>; Department of Internal Medicine and.; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Storck+WK%22">Storck WK</searchLink>; Department of Internal Medicine and.; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Kuleape+JA%22">Kuleape JA</searchLink>; Department of Internal Medicine and.; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Bedi+K%22">Bedi K</searchLink>; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.; Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Mannan+R%22">Mannan R</searchLink>; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Wang+XM%22">Wang XM</searchLink>; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Michigan Center for Translational Pathology, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Udager+A%22">Udager A</searchLink>; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Ravikumar+V%22">Ravikumar V</searchLink>; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Bankhead+A+3rd%22">Bankhead A 3rd</searchLink>; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Coleman+I%22">Coleman I</searchLink>; Divisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Lee+JK%22">Lee JK</searchLink>; Divisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Morrissey+C%22">Morrissey C</searchLink>; Department of Urology, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Nelson+PS%22">Nelson PS</searchLink>; Divisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Chinnaiyan+AM%22">Chinnaiyan AM</searchLink>; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Michigan Center for Translational Pathology, Ann Arbor, Michigan, USA.; Department of Urology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Howard Hughes Medical Institute, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Rao+A%22">Rao A</searchLink>; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.; Department of Radiation Oncology and.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Xia+Z%22">Xia Z</searchLink>; Knight Cancer Institute and.; Biomedical Engineering Department, Oregon Health & Science University (OHSU), Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Yates+JA%22">Yates JA</searchLink>; Department of Internal Medicine and.; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Alumkal+JJ%22">Alumkal JJ</searchLink>; Department of Internal Medicine and.; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.; Michigan Center for Translational Pathology, Ann Arbor, Michigan, USA.
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  Data: <searchLink fieldCode="JN" term="%22101676073%22">JCI insight</searchLink> [JCI Insight] 2023 Aug 08; Vol. 8 (15). <i>Date of Electronic Publication: </i>2023 Aug 08.
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