Phase 1 safety, tolerability, pharmacokinetics and pharmacodynamic results of KCL-286, a novel retinoic acid receptor-β agonist for treatment of spinal cord injury, in male healthy participants.
Saved in:
| Title: | Phase 1 safety, tolerability, pharmacokinetics and pharmacodynamic results of KCL-286, a novel retinoic acid receptor-β agonist for treatment of spinal cord injury, in male healthy participants. |
|---|---|
| Authors: | Goncalves MB; Neuroscience Drug Discovery Unit, The Wolfson Centre for Age-Related Diseases, King's College London, Guy's Campus, London, UK., Mant T; NIHR Biomedical Research Centre at Guy's and St Thomas' NHS Foundation Trust and King's College London, Guy's and St Thomas' NHS Foundation Trust, London, UK., Täubel J; Richmond Pharmacology Limited, London, UK., Clarke E; Neuroscience Drug Discovery Unit, The Wolfson Centre for Age-Related Diseases, King's College London, Guy's Campus, London, UK., Hassanin H; Surrey Clinical Research Centre, University of Surrey, Surrey, UK., Bendel D; Surrey Clinical Research Centre, University of Surrey, Surrey, UK., Fok H; NIHR Biomedical Research Centre at Guy's and St Thomas' NHS Foundation Trust and King's College London, Guy's and St Thomas' NHS Foundation Trust, London, UK., Posner J; Centre for Pharmaceutical Medicine Research, Institute of Pharmaceutical Science, King's College London, London, UK., Holmes J; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Mander AP; Centre for Trials Research, Cardiff University, Cardiff, UK., Corcoran JPT; Neuroscience Drug Discovery Unit, The Wolfson Centre for Age-Related Diseases, King's College London, Guy's Campus, London, UK. |
| Source: | British journal of clinical pharmacology [Br J Clin Pharmacol] 2023 Dec; Vol. 89 (12), pp. 3573-3583. Date of Electronic Publication: 2023 Aug 09. |
| Publication Type: | Randomized Controlled Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 1365-2125 |
|---|---|
| DOI: | 10.1111/bcp.15854 |
