The predominant PAR4 variant in individuals of African ancestry worsens murine and human stroke outcomes.

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Title: The predominant PAR4 variant in individuals of African ancestry worsens murine and human stroke outcomes.
Authors: Denorme F; Program in Molecular Medicine and.; Department of Neurology, Division of Vascular Neurology, University of Utah, Salt Lake City, Utah, USA., Armstrong ND; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA., Stoller ML; Program in Molecular Medicine and., Portier I; Program in Molecular Medicine and., Tugolukova EA; Program in Molecular Medicine and., Tanner RM; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA., Montenont E; Program in Molecular Medicine and., Bhatlekar S; Program in Molecular Medicine and., Cody M; Program in Molecular Medicine and., Rustad JL; Program in Molecular Medicine and., Ajanel A; Program in Molecular Medicine and., Tolley ND; Program in Molecular Medicine and., Murray DC; Program in Molecular Medicine and., Boyle JL; Bioinformatics Shared Resource, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA., Nieman MT; Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, USA., McKenzie SE; Department of Medicine, The Cardeza Foundation for Hematologic Research, Thomas Jefferson University, Philadelphia, Pennsylvania, USA., Yost CC; Program in Molecular Medicine and.; Department of Pediatrics, Division of Neonatology, University of Utah, Salt Lake City, Utah, USA., Lange LA; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Cushman M; Department of Medicine, Larner College of Medicine at the University of Vermont, Burlington, Vermont, USA., Irvin MR; Department of Neurology, Division of Vascular Neurology, University of Utah, Salt Lake City, Utah, USA., Bray PF; Program in Molecular Medicine and.; Department of Internal Medicine, Division of Hematology and Hematologic Malignancies, and., Campbell RA; Program in Molecular Medicine and.; Department of Internal Medicine, Division of Hematology and Hematologic Malignancies, and.; Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, Utah, USA.
Source: The Journal of clinical investigation [J Clin Invest] 2023 Sep 15; Vol. 133 (18). Date of Electronic Publication: 2023 Sep 15.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1558-8238
DOI:10.1172/JCI169608